Search found 56 matches

by PittieLady
Tue Jul 26, 2022 11:27 pm
Forum: Polls
Topic: Orgasms' pleasure intensity (while on SRIs)
Replies: 17
Views: 15524

Re: Orgasms' pleasure intensity (while on SRIs)

I think he is talking about buspirone...is that right arahunt?
by PittieLady
Fri Jan 07, 2022 12:56 am
Forum: Polls
Topic: Orgasms' pleasure intensity (while on SRIs)
Replies: 17
Views: 15524

Re: Orgasms' pleasure intensity (while on SRIs)

This is my number 1 issue. Also took setraline on and off for years. Went 10 years off and it made no difference. I am interested I'm the theories here around if it's the brain, spinal cord etc
by PittieLady
Thu Jan 28, 2021 8:47 pm
Forum: Treatments and experimentation
Topic: PSSD for 3 years, corticosteroids temporarily cured all PSSD symptoms
Replies: 79
Views: 23920

Re: PSSD for 3 years, corticosteroids temporarily cured all PSSD symptoms

Im really interested in this because I have adrenal insufficiency....my adrenals dont work so i take 2x daily hydrocortisone. My orgasms totally suck...best orgasms are oddly under pressured situations and few and far between. Weird thing is is that women (i am one) with adrenal insufficiency have n...
by PittieLady
Mon Jan 04, 2021 8:03 pm
Forum: General
Topic: Has anyone specifically regained the ability to have a pleasurable orgasm?
Replies: 37
Views: 8873

Re: Has anyone specifically regained the ability to have a pleasurable orgasm?

I started upping my buspar and have definitely noticed a couple things. 1. For the first time in like forever I am having vivid dreams and I remember them all. I cant remember the last time I remembered my dreams and for 3 days in a row since upping I have detailed recollection of my dreams. 1 of th...
by PittieLady
Thu Dec 24, 2020 7:54 am
Forum: General
Topic: Has anyone specifically regained the ability to have a pleasurable orgasm?
Replies: 37
Views: 8873

Re: Has anyone specifically regained the ability to have a pleasurable orgasm?

Thanks arahant! I am going to try to up the dose. Realizing too my biggest dose it literally right before i go to bed so thats not overly helpful. Appreciate the info.

And @anhedonia- thats amazing. I did wellbutrin for a while and had no positive effects. Glad it helped you.
by PittieLady
Wed Dec 23, 2020 6:47 pm
Forum: General
Topic: Has anyone specifically regained the ability to have a pleasurable orgasm?
Replies: 37
Views: 8873

Re: Has anyone specifically regained the ability to have a pleasurable orgasm?

Thank you all for answering. I will definitely ask my doctor about Buspirone. There's a company just researching how to optimize the dosing schedule for better results, also combining with other pro-sexual agents. But the combination is not approved for sales yet. https://www.nature.com/articles/d4...
by PittieLady
Fri Jan 10, 2020 11:12 pm
Forum: General
Topic: What drug most increased genital sensitivity for you?
Replies: 21
Views: 8613

Re: What drug most increased genital sensitivity for you?

I don't have an answer but am in the same boat that I'd love feedback on whats helped people in this arena If this alone improved for me, I could live with this and the lack of desire to have sex with others. The weak/pleasureless orgasms are the bane of my existence. Anyone heard of nickel impactin...
by PittieLady
Thu Oct 31, 2019 9:12 pm
Forum: Treatments and experimentation
Topic: Cure attempt #2 (in-progress / initial findings)
Replies: 77
Views: 32347

Re: Cure attempt #2 (in-progress / initial findings)

Hey meso! Got really excited reading this but then looked back at a neurotransmitter test i had done like 4 or 5 years ago that showed i have low serotonin and normal range glutamate. Would this not be appropriate then? Would obviously wait anyway in light of you still testing but just curious
by PittieLady
Sun Sep 29, 2019 9:53 am
Forum: PSSD related research
Topic: Genital numbness/anesthesia: the science
Replies: 7
Views: 3682

Re: Genital numbness/anesthesia: the science

Great article! Meso can you talk about whats needed to do this? Supplements that help? Another thing we can do is improving glutamate firing. SSRIs upregulate GR expression, leading to blunting of HPA axis. Cortisol is a glutamate enhancer, so you end up with less glutamate firing and beta-endorphin...
by PittieLady
Sun Sep 29, 2019 9:23 am
Forum: Treatments and experimentation
Topic: Peptides
Replies: 9
Views: 3533

Re: Peptides

Im interested in this too. Just joined the fb group as i have lyme, cos, autoimmune and pssd. Semax and selank are interesting...looking for something to help w depreasion and anxiety; vortioxitine is conking out for me a bit