anyone given this a good try??

endorhins block serotonin the the brain......i know my symptoms improve alot when i have endorphins raging

if you search this document for sensiti it bring up 4 results, I havent read the whole thing yet, but this paragraph seems improtant..... indicatingthat 5-HT2Creceptor also exerts a tonic and phasic inhibitory control on mesolimbic DA neuron activity [112] . The observa- tion that SB206553-stimulate...

Hi, and this is particularly to Sonny, but please anyone else that can answer please do.... Sonny, you spoke in another thread that we want LESS 5ht1 receptors?? why is this? surely if we had MORE 5ht1 receptors then we have a larger amount to work on to inhibit the release of serotonin post synapti...

many thanks ghost Sonny, its hard not to get defensive, as im sure you would be if someone gave you the same answer to your issues This is 100% from taking an ssri, its happened to hundreds and hundreds of people, im not alone.....gaba effecting things do not effect me, anything that raises werotoni...

I cant find the thread Im trying to find.....someone had written about the chamical changes and reasons that dating again could improve pssd, i found this with my symptoms, was it something to do with oxytocin being released? how does that impact serotonin?

sorry guys, no one has had a good read of my first set of questions and here i am with some more 1) is there not a 5ht1 agnoist that is not an agonist of 5ht2? i cannot tolerate anything that increases serootnin to 5ht2 with the tardive akathisia 2) would using an agonist on 5ht1 long term not conti...

if im correct in my thinking, even if DAT does take up serotonin when there is too much, reducing the serotonin via 5ht1 would stop that...my issue has been from citaloprm though and i would be interested to read the study if you could link to it please

oh and heres another question...if the 5ht2 and 3 receptors are flooded with serootnin due to the desensitisation of 5ht1...then why wouldnt those receptors just downregulate in response and stop the problem?

so to summerise, my main questions are thses 1) what does citalopram downregulate and has anyone had pssd happen months after stoppping? 2) how can cannabis casue a great improvement but after constant use turn into severe worstening? 3) why would i gotten so much worse months after stopping, what u...

Hi everyone allow me to begin by saying that I dont have PSSD..lucky me eh? wrong.....I have severe chronic and life ruining symptoms all related to the stopping and then an adverse reaction to citalopram the reason I like this forum is becasue here at least people are looking for answers, and there...