Search found 6 matches
- Tue Sep 27, 2022 5:55 am
- Forum: PSSD related research
- Topic: An Excellent Explaination of How SSRI's Inhibit Sert
- Replies: 85
- Views: 88563
Re: An Excellent Explaination of How SSRI's Inhibit Sert
fluvoxamine increases Akt-phosphorylation through sigma1-receptors [180,181], while sertraline decreases it [182]. Sertraline inhibition of Akt leads to more gsk3b expression which causes less canonical wnt activation and decrease sert expression through changes in microrna. It probably explains wh...
- Mon Oct 12, 2020 5:44 am
- Forum: Treatments and experimentation
- Topic: Success report of someone using St. John's Wort Ze 117 (0.2% hyperforin)
- Replies: 3
- Views: 1132
Re: Success report of someone using St. John's Wort Ze 117 (0.2% hyperforin)
the benefits were temporary and didn't cure him
he got pssd from ashwagandha which alters 5ht1a
he got pssd from ashwagandha which alters 5ht1a
- Thu May 07, 2020 12:59 pm
- Forum: Treatments and experimentation
- Topic: Inositol or SJW ?
- Replies: 2
- Views: 1051
Inositol or SJW ?
I took Maprotiline 10 mg( micro dose) for 5 days 6 months ago which is a 5HT2A antagonist, so I don't think I have 5HT1A desensitization because i took a really small dose for a short time. my symptoms are emotional numbness, fatigue, severe brain fog and sexual dysfunction( thick semen, lower libid...
- Wed Jan 15, 2020 1:08 pm
- Forum: Treatments and experimentation
- Topic: should I take or stay away from Testosterone Injections ?
- Replies: 11
- Views: 3241
Re: should I take or stay away from Testosterone Injections ?
will it shut down sperm production 3 times in 9 weeks ? (for short-term use only)
- Tue Jan 14, 2020 11:50 pm
- Forum: Treatments and experimentation
- Topic: should I take or stay away from Testosterone Injections ?
- Replies: 11
- Views: 3241
Re: should I take or stay away from Testosterone Injections ?
I was on ludiomil (TCA) 10mg for 5 days then stopped takning it and I got pssd and anhedonia since then. one month later I took Escitalopra 5mg for 3 days and stopped taking it too because it made me nervous. it has been 3 months I have't taken anything. my erection and genital numbness improved but...
- Tue Jan 14, 2020 4:01 pm
- Forum: Treatments and experimentation
- Topic: should I take or stay away from Testosterone Injections ?
- Replies: 11
- Views: 3241
should I take or stay away from Testosterone Injections ?
I am 21M shbg : 24.81 nmol/l Free Testosterone : 0.901 nmol/l Total Testosterone : 22.36 nmol/l Vitamin D3 : 38.58 ng/ml Vitamin B12: 172.4 pg/ml My symptoms : Low sex drive anhedonia and Emotional blunting/ numbness ( cant feel fear, love, hate, happiness, sadness) back muscle pain. low energy weak...