Hello,
I have negative experience with naltrexone. Having heard about it I decided to try. I had taken one pill (50 mg) and my barely existent libido vanished at all for a weak.
How long did you take it before you got improvements?

Honestly propeciahelp mods did more damage to the community than they helped. When people believe this stupid AR and epigenetic change theory, which is totally absurd, people tend to get stuck in a thought loop that there is no way out. Thats how suicides happen. Just look at poor anhedonicape and ...

pssd could be caused by autoimmune recation for example
https://berlincures.de/new-paper/
" DNA-Based Drug BC 007 neutralizes agonistically acting autoantibodies directed against G protein–coupled receptors "
allmost all serotonin receptors are GPCR

I have tried clomipramine for a month... this is quite a long story. I will add my intro soon

I dont know is it better or not. I just dont have such a strong PE now.It has been two years since I got pssd and I have not expierenced any windows or crashes since. I still have a very severe ED.

I had been expierencing PE during the first year of my pssd induced by venlafaxine. It was so bad I could even ejaculate without an erection.

@guacamo what makes some people more vulnerable to develop pssd considering your theory?

" IC50 for 5-HT7 receptor for serotonin " -??

Do you have ED?

Hi Meso. Did you abandon your water fasting trial?