Search found 21 matches
- Thu May 27, 2021 4:29 pm
- Forum: Treatments and experimentation
- Topic: Reports of use of mirtazapine
- Replies: 14
- Views: 4016
Re: Reports of use of mirtazapine
My hope is i can get good improvements in depression/pssd from mirtazapine without anxiety. Its noradrenergic activity can cause anxiety in me, as it has in the past. but ive never tried low dose. Looking to capitalize on its activty at 5ht1a, 2a, and 2c for depression/pssd
- Thu May 27, 2021 3:33 pm
- Forum: Treatments and experimentation
- Topic: Reports of use of mirtazapine
- Replies: 14
- Views: 4016
Re: Reports of use of mirtazapine
really, that is fascinating. i am undergoing ketamine treatment right now and am noticing a worsening of symptoms. Does your ketamine doc give you ondansetron before sessions? I have found 5ht3 antagonists worsen my symptoms substantially and i think the worsening of symptoms may be due to the ondan...
- Tue May 25, 2021 2:27 pm
- Forum: Treatments and experimentation
- Topic: Reports of use of mirtazapine
- Replies: 14
- Views: 4016
Re: Reports of use of mirtazapine
What benefits did you experience in regards to both depression and pssd? I'm consideringtrying 7.5 mg for help with depression/pssd
Also, have you experienced any rebound depression/pssd since coming off? Did you switch to something else or just stop mirtazapine?
Also, have you experienced any rebound depression/pssd since coming off? Did you switch to something else or just stop mirtazapine?
- Mon May 24, 2021 10:48 pm
- Forum: Treatments and experimentation
- Topic: Reports of use of mirtazapine
- Replies: 14
- Views: 4016
Re: Reports of use of mirtazapine
how much weight gain did it cause and what dosage were you on?sovietxrobot wrote: ↑Wed Mar 03, 2021 11:19 am Its an antagonist of 5ht2a and 2c so it sounds reasonable for treatment of PSSD. In practice it wasn't as good as I had hoped. It gave me some symptom relief that faded quickly. I'm quitting now because the weight gain is intolerable.
Re: Kava Kava
does zero for pssd. maybe even makes it worse
- Mon May 24, 2021 7:23 pm
- Forum: Treatments and experimentation
- Topic: Experience with Kratom?
- Replies: 5
- Views: 1949
Re: Experience with Kratom?
kratom crashes me hard
- Sat May 22, 2021 10:20 pm
- Forum: Treatments and experimentation
- Topic: My theory
- Replies: 26
- Views: 6940
Re: My theory
So if it’s more about signaling and not amount available how do we correct that? If you guys are right, what is to be done, what do we try? I think several of us would be willing to test this theory if we knew what to try. I would have to monitor your results individually, after making a few sugges...
- Fri May 21, 2021 1:36 am
- Forum: Speculations and hypotheses
- Topic: Very very soft penis
- Replies: 7
- Views: 2871
Re: Very very soft penis
how to treat it?
- Fri May 21, 2021 1:22 am
- Forum: Speculations and hypotheses
- Topic: Postsynaptic AMPA receptor upregulation?
- Replies: 12
- Views: 5093
Re: Postsynaptic AMPA receptor upregulation?
Any updates on this? Fascinating thread. Meso, are you saying that metformin would block the antidepressant effects of ketamine?
- Fri May 07, 2021 8:42 pm
- Forum: Treatments and experimentation
- Topic: Thoughts on 5HT1A antagonists?
- Replies: 52
- Views: 12697
Re: Thoughts on 5HT1A antagonists?
5ht1a antagonists will probably not sensitize the receptor because there is a large concentration of serotonin in our synapses from sert down regulation. Antagonists will just increase 5ht firing, by blocking 5ht1a receptors, which will worsen symptoms. We need to focus on finding ways to upregulat...