Cyproheptadine completely cures all my symptoms for a single day 5 days after acute dosing. As for your question on long term improvement... the effect seems additive and can provide long term improvements with microdoses after a full dose rebound. The catch is you have to be able to put up with the...

It wasn’t the cypro. Cypro takes 2-4 hours to kick in with only 4mg. Even in cases where large amounts are used for serotonin syndrome it still takes an hour for effects. That’s very odd then. Could it be that I wasn’t experiencing serotonin syndrome but some weird effects from the ALCAR 5ht1a agon...

It wasn’t the cypro. Cypro takes 2-4 hours to kick in with only 4mg. Even in cases where large amounts are used for serotonin syndrome it still takes an hour for effects.

Hello, I'm back again sadly with bad news. Because of my NSI-189 induced neuropathy, I was taking a B complex, alpha lipoic acid, magnesium, and algae oil (omega 3) to make sure I had enough of them despite my average diet. I started the stack at the beginning of August. Around mid-August, I stoppe...

I was about to make my own thread on intracellular calcium release for this pathway but found this one. That being said I would like to revive this thread. I am able to make the Cypro rebound come a day earlier or strengthen it with inositol. I am also able to replicate it with megadoses of quercit...

I was about to make my own thread on intracellular calcium release for this pathway but found this one. That being said I would like to revive this thread. I am able to make the Cypro rebound come a day earlier or strengthen it with inositol. I am also able to replicate it with megadoses of querciti...

I tried Cyproheptadine 2 years ago. Long story short, I had a strange experience on it where, completely unstimulated, I had the stomach tensing part of an orgasm, with no physical sensation in my genitals. It was like half of an orgasm - really weird. Full post - https://pssdforum.org/viewtopic.ph...

Cypro is brilliant. I take 2 or 4 mg 3 hours before bed for 2-3 days. Sensation comes back almost immediately. Emotional blunting is resolved days after quitting once the rebound kicks in. Emotional blunting is only ever fixed for a couple days but sensation lasts a week or so and seems to set a sli...

Don't obsess with getting to 100%, but try to live a rewarding life with everything you have spared. Occasional ( 2x per week ) methylphenidate seems safe, chronic daily may cause problems. Vortioxetine is the worst option possible. Reistantation is only advisable if your OCD is so bad you cannot l...

Have you trialed CBG and what were the results? I take 10-20mg about 3 times a week before bed. Granted I take all antagonists and almost all meds helpful for PSSD at bed otherwise they don’t do anything for me. It’s effective. I’m a non-responder to agonists because I’ve been desensitized/had PSSD...