Interesting. Did Spyros ever discontinue the E2 therapy or is he still taking it? I wonder if using something less invasive, like resveratrol for example, could help? As it can increase estrogen receptor beta activity while not disturbing the ERa subtype, the most concerning one. Perhaps someone cou...

Interesting protocol, certainly unorthodox. I'm not apart of the discord group. Did he by chance elaborate on why he thought the E2 treatment worked so well? I do remember reading a long time ago in a study (on animals) that estradiol lowered the amount of presynaptic 5-HT1A (autoreceptor) in the hy...

Thanks, I appreciate the advice. I actually think my issue started before I got on SSRI medication. It's so hard to explain how uncharacteristic anxiety was for me before this problem arose. I never used to get panic attacks. It's like I did something one day that just flipped a switch that I can't ...

I've recently just found this forum for the first time. Kind of refreshing to see a new place talking about some of this stuff. Happy to be here, and I would like to discuss further topics relating to PSSD. I don't think all of my problems extend from this condition, but I do think and extensive amo...