Search found 448 matches

by cdraham
Mon Apr 18, 2022 6:53 am
Forum: PSSD related research
Topic: Serotonin transporter deficiency drives estrogen-dependent obesity and glucose intolerance
Replies: 13
Views: 2097

Re: Serotonin transporter deficiency drives estrogen-dependent obesity and glucose intolerance

Tree wrote: Sun Apr 17, 2022 8:00 pm I believe hormone/metabolic changes are downstream effects of sert loss. You reverse the sert inhibition and everything else will start to normalize.
Do we have any practical way to reverse SERT loss? I think evodiamine and berberine was tried by many
by cdraham
Fri Apr 08, 2022 8:36 am
Forum: Treatments and experimentation
Topic: Pindolol - Preference for pre-synaptic 5ht1a
Replies: 2
Views: 844

Re: Pindolol - Preference for pre-synaptic 5ht1a

You could also probe by taking DXM, reboxetine, or a antipsychotic which strongly agonizes 5ht1a - should give us window of emotional function
by cdraham
Wed Mar 30, 2022 11:53 am
Forum: Treatments and experimentation
Topic: 25 PSSD success stories with steroids (plus 12 PFS/PAS cures)
Replies: 30
Views: 33496

Re: List of 20 success stories with steroids

Joao Paulo Brasil wrote: Wed Mar 30, 2022 11:25 am I've been at it for three weeks. and so far my libido is still zero, the only thing i noticed is that my morning erection has been returning for a few days now.
Trestolone? Or what are you using? Are you combining it with lithium?
by cdraham
Wed Mar 30, 2022 10:08 am
Forum: Treatments and experimentation
Topic: 25 PSSD success stories with steroids (plus 12 PFS/PAS cures)
Replies: 30
Views: 33496

Re: List of 20 success stories with steroids

Did someone try running some trestolone along with test for some time?
by cdraham
Sun Mar 13, 2022 9:39 pm
Forum: New Member Intros
Topic: AnhedonicApe - Intro
Replies: 163
Views: 36182

Re: AnhedonicApe - Intro

fucking legend.. RIP
by cdraham
Tue Jan 25, 2022 10:42 am
Forum: General
Topic: Tryptophan metabolism, LPS, etc..
Replies: 6
Views: 1332

Re: Tryptophan metabolism, LPS, etc..

Serotonin Activates Bacterial Quorum Sensing and Enhances the Virulence of Pseudomonas aeruginosa in the Host https://www.ncbi.nlm.nih.gov/labs/pmc/articles/PMC4972532/ Natural Compounds Inhibiting Pseudomonas aeruginosa Biofilm Formation by Targeting Quorum Sensing Circuitry https://www.intechopen....
by cdraham
Mon Jan 24, 2022 6:50 pm
Forum: General
Topic: Tryptophan metabolism, LPS, etc..
Replies: 6
Views: 1332

Re: Tryptophan metabolism, LPS, etc..

I didn't found genital numbess for lyme disease, so don't think we can relate for it Gut dybiosis can look very similiar to lyme disease, when LPS gets into the bloodstream. Also you could have lyme on top of PSSD I got lyme before pssd. Lyme community is large and no one aswer they have gentital n...
by cdraham
Mon Jan 24, 2022 6:44 pm
Forum: General
Topic: Tryptophan metabolism, LPS, etc..
Replies: 6
Views: 1332

Re: Tryptophan metabolism, LPS, etc..

Integra wrote: Mon Jan 24, 2022 6:42 pm I didn't found genital numbess for lyme disease, so don't think we can relate for it
Gut dybiosis can look very similiar to lyme disease, when LPS gets into the bloodstream. Also you could have lyme on top of PSSD
by cdraham
Mon Jan 24, 2022 5:23 pm
Forum: General
Topic: Tryptophan metabolism, LPS, etc..
Replies: 6
Views: 1332

Tryptophan metabolism, LPS, etc..

https://www-mikrooek-de.translate.goog/labordiagnostik/fuer-aerzte-und-therapeuten/schleimhaut-diagnostik/silent-inflammation/?_x_tr_sl=auto&_x_tr_tl=en&_x_tr_hl=en sorry this is google translate probably the most useful lab test I came across for PSSD My kynurenine is also high other useful...