I have very similar issues with thyroid. I have low body temp and slow metabolism and higher tsh. But I cannot tolerate thyroid meds. I get a horrible wired but tired feeling after about a week. And I get horrendous tooth and fingertip sensitivity. It seems thyroid without another component not wor...

Only registered members can view the text of the link that you posted. Anyways, is it saying that this drug increases the amount of time it takes for a man to cum? Because SSRIs and other antidepressants have that same effect. It’s saying 5HT1A is important to prevent premature ejaculation. I’m not...

It’s a research 5HT1A antagonist that has reversed SSRI induced sexual dysfunction in rats

https://www.practiceupdate.com/content/effect-of-single-oral-dose-of-5-ht1a-antagonist-gsk958108-on-ejaculation-latency-time/109930 Effect of Single Oral Dose of 5-HT1A Antagonist GSK958108 on Ejaculation Latency Time “ The authors assessed the efficacy of a single dose of a serotonin (5HT1A) recept...

https://pubmed.ncbi.nlm.nih.gov/29451186/ “Lactobacillus acidophilus and Bifidobacterium longum supernatants upregulate the serotonin transporter expression in intestinal epithelial cells Conclusions: L. acidophilus and B. longum supernatants can upregulate SERT mRNA and protein levels in intestinal...

My glucose levels are high too. 5ht1a receptors suppress glucose levels in the brain via pka inhibition which activates ampk. 5ht1a antagonists increase glucose/insulin levels by inhibiting ampk via pka activation. This gives me another reason to believe 5ht1a receptors are desensitized, besides cr...

I have developed some paranoia around anything I ingest since I’m scared it could make my anhedonia/pssd worse. And recently Ive been wanting to try a new organic decaf coffee brand I bought made from bourbon and carturra coffee beans, yet I’m scared since I’ve never had those type of coffee beans j...

I also have this question, did you ended up taking it?

I blame a lot the people who drove me to take SSRIs, like the abusive relationship I was in that made me develop strong anxiety and have to see a psychiatrist. It breaks me to thing the power he had over me to the point I got literally damaged by drugs I took to deal with his bs. But I also blame do...

No, but I'll have to do that. The study mentions various metabolic issues associated with serotonin transporter Tree, could you do something about your high insulin? I have the same issue, very high insulin and low to normal blood sugar. I also follow a very healthy diet, no reason why my insulin w...