That's a great study Kinn. I have some forskolin on the way, to use alongside the metergoline.

Have you obsevered any other changes than happier balls? Has your eyesight improved? Is it clearer or something? What about brain fog? Has it lifted (of course as far as you have some)? Is your anhedonia already getting better? Has your mood improved? Can you feel an antidepressant effect? Yeah, ac...

Yeah, i think SSRIs will very likely affect your steroid synthesis, for one thing serotonin overload will jack up cortisol, which will hinder normal steroid production; https://www.ncbi.nlm.nih.gov/pubmed/8382638 The LH-->5HT-->CRF inhibitory loop serves to continuously buffer the stimulation of and...

Man, i'm sorry to hear about your struggles. I like you have trouble feeling many things at all but i can at least sympathize with you having to deal with this crap. Yeah DHEA + pregnenolone haven't produced miracles for me, but it has been a component to my testicles going from total shrinkmode bac...

Sertraline is indeed a bad guy. https://www.ncbi.nlm.nih.gov/pubmed/24642156 I also took that shit pill for a good two years. I've only done T reading once, a few months ago, after following recommendations on this site for a while https://www.anabolicmen.com/ Total T was 38 nmol/L (1096 ng/dl), SHB...

Hm, i was sure i saw a PM-button. Anyway, this is the source; http://idealabsdc.com/lab/

Alright, cool! Thanks for the details on dosing. Anhedonia going away sounds like a good thing. Have you seen any changes in testicle size? (If it was ever a problem for you) Mirtazapine (Mianserin with an extra nitrogen atom) made my testicles swell up. Never did much for libido though. How much ar...

Nice, thanks for those studies Kinncrimson. At how high dose did you take mianserin? I'm thinking i should ask my doctor for it, or try mirtazapine again. About the same time this thread was created a source for metergoline was made avaliable, i've tried it for two days now. Balls seem slightly happ...

Long-term exposure of RN46A cells expressing serotonin transporter (SERT) to a cAMP analog up-regulates SERT activity and is accompanied by neural differentiation of the cells.
https://www.ncbi.nlm.nih.gov/pubmed/23269237

Whew... Unless you're already gone - i'm not at all familar with neurofeedback, but i guess some professional/doctor was aiding you - did they have any comments about what you found? SERT being a major/the major culprit makes sense as that's the main target for these darn poisons. I agree that focus...