Search found 57 matches

by Zero
Sun Jul 24, 2016 6:16 am
Forum: Polls
Topic: can you feel love?
Replies: 20
Views: 11053

Re: can you feel love?

Yes, I can.
by Zero
Thu Jul 07, 2016 5:35 am
Forum: General
Topic: 100% fine now*
Replies: 24
Views: 16421

Re: 100% fine now*

Honestly, could you ELABORATE something more? Like symptoms, meds, your progress, timeline?
by Zero
Thu Jul 07, 2016 3:17 am
Forum: New Member Intros
Topic: Sertraline induced PSSD
Replies: 51
Views: 21609

Re: Sertraline induced PSSD

I'm in the same boat. I'd been on 100mg for 6 years and I'm recovering (slowly). First thing relax, stress will slow down your progress. 50mg for one month is next to nothing, you'll get better, eat healthy, do some cardio, meditate, sleep well. It wouldn't be a bad idea to check your hormones: thyr...
by Zero
Sun Jul 03, 2016 5:26 am
Forum: General
Topic: I posted this study in Reddit's Science subreddit and it exploded in popularity and then got removed
Replies: 3
Views: 2317

Re: I posted this study in Reddit's Science subreddit and it exploded in popularity and then got rem

Greed had eaten ethics long time ago. Our ultimate goal (besides recovery ofc) namely permanent post SSRI sexual dysfunction as a side effect of SRIs printed on the drug leaflet means big $$$ loses. Will never happen. Ghost, keep an eye on big pharma's assassins. :roll:
by Zero
Fri Jul 01, 2016 4:29 pm
Forum: General
Topic: Can MDMA cause same thing as PSSD?
Replies: 14
Views: 8839

Re: Can MDMA cause same thing as PSSD?

For me there are three keywords: persisting serotonin neurotoxicity. Cognitive, or sexual impairment, doesn't matter.
by Zero
Fri Jul 01, 2016 2:32 pm
Forum: General
Topic: Can MDMA cause same thing as PSSD?
Replies: 14
Views: 8839

Re: Can MDMA cause same thing as PSSD?

Brain Serotonin Function in MDMA (Ecstasy) Users: Evidence for Persisting Neurotoxicity http://www.nature.com/npp/journal/v38/n1/full/npp2012178a.html Animal models suggest that MDMA causes chronic serotonin neurotoxicity , especially in neocortex. Studies examining the presynaptic serotonin reupta...
by Zero
Fri Jul 01, 2016 4:53 am
Forum: General
Topic: When I take back Abilify, I have a slight and temporary improvement in PSSD.
Replies: 14
Views: 6246

Re: When I take back Abilify, I have a slight and temporary improvement in PSSD.

Everything is here, I'm repeating myself:

http://www.pssdforum.com/viewtopic.php?f=10&t=694

Serotonin increases SERT, most likely resensitizes 5-HT1A. Shamely temporary.
by Zero
Fri Jul 01, 2016 4:50 am
Forum: General
Topic: When I take back Abilify, I have a slight and temporary improvement in PSSD.
Replies: 14
Views: 6246

Re: When I take back Abilify, I have a slight and temporary improvement in PSSD.

I would say the whole PSSD problem lies more in the gene expression of SERT than anything else . I think I read that Bacopa Increases SERT expression in the hippocampus which returns to baseline after 52 days meaning it is temporary.s but moreover it significantly increases serotonin and decreases ...
by Zero
Fri Jul 01, 2016 4:28 am
Forum: General
Topic: Can MDMA cause same thing as PSSD?
Replies: 14
Views: 8839

Re: Can MDMA cause same thing as PSSD?

Probably. Increased Anxiety 3 Months after Brief Exposure to MDMA ('Ecstasy') in Rats: Association with Altered 5-HT Transporter and Receptor Density http://www.nature.com/npp/journal/v28/n8/full/1300185a.html High-dose MDMA produces loss of SERT binding sites in rats (Battaglia et al, 1991,1987; Le...