The effects are mild because brain is plastic and compensate the lack of serotonin signalling with other transmission. You see this things all the time in knouckout gene experiments. In neuroanatomy even removing entire lobe ( like in epilepsy ) gives limited symptoms, because - again - brain is pl...

Had moderate success with 100mg-500mg Cubensis doses. I will take it and the next few days after my PSSD will be significantly better. Still experimenting with it.

Any updates? Sorry for all the delays on the update. Here's a quick summary of what I did. Started at 20mg 1/day, ramped up over a few days to 1g 3x/day. The side effects are probably not what one would expect, I would say the top one that was an annoying vertigo, this is a feeling I had only felt ...

ErgogenicHealth wrote: ↑Sat Mar 20, 2021 1:35 am Curious to hear the end of this report... How are you feeling now?
When I NUKED serotonin with Cyproheptadine microdose, or BCAA + Tyrosine combo, I actually felt worse.

When i tried cyproheptadine it helped me a bit, but not as much as mianserin. I dont think microdosing those is the way to go.

As far as I know, fenclonine is a suicide inhibitor, meaning that you only need to take once every few days, no point in using it daily. Keep us updated with the side effects too. If it doesn't make you depressed, then that means your dopamine signaling is doing a great job, even in total absence o...

As far as I know, fenclonine is a suicide inhibitor, meaning that you only need to take once every few days, no point in using it daily. Keep us updated with the side effects too. If it doesn't make you depressed, then that means your dopamine signaling is doing a great job, even in total absence o...

Currently on 3g/day, it is surprisingly tolerable. Effect on drive is very minimal thus far. This is acute intake, I'm wondering what happens if you take this for a month or so and some neuroplasticity starts kicking in. Very interesting trial! although I highly doubt that lowering serotonin (alone)...

Posting this while doing the experiment, will do a report afterwards. Been ramping up the dosage the last few days, now at 1g/day, planning on going up to 2g, continuing it for a few more days then stop. First 2 days at 100mg had me feeling weird, but now the noticeable effects are very minimal. Per...

Is there any study done on humans with this drug we could read on?

I created a post on the PSSDlab site with links to every possible treatment thread ever posted in the treatments section. Some are repeats, but that just means that there is more than one thread on the same topic :x . I'm going to sticky this to the top of this forum. READ IT TO MAKE SURE THAT YOUR...