Search found 265 matches

by PsychoGenesis
Sat Nov 14, 2020 12:32 pm
Forum: PSSD related research
Topic: Anyone else have the gene Gs224 (causes low dopamine)?
Replies: 7
Views: 1734

Re: Anyone else have the gene Gs224 (causes low dopamine)?

myheritage data doesn't show this one for me


have you tried taking tyrosine??
by PsychoGenesis
Thu Nov 12, 2020 1:46 pm
Forum: General
Topic: Drugs/supplements that improves pssd permamently.
Replies: 19
Views: 5363

Re: Drugs/supplements that improves pssd permamently.

my bad, It's the other way around

psychedelics also seem to upregulate them
but it's hard to judge cumulative benefits
by PsychoGenesis
Wed Nov 11, 2020 10:36 am
Forum: New Member Intros
Topic: PSSD ?
Replies: 122
Views: 52125

Re: PSSD ?

mucuna is labeled by Ldopa %


yohimbine interacts with many 5ht receptors it's like a 🔨
by PsychoGenesis
Tue Nov 10, 2020 8:33 pm
Forum: Treatments and experimentation
Topic: CBG/Cannabigerol For PSSD Is HELPING me!!! (Huge potential)
Replies: 21
Views: 7278

Re: CBG/Cannabigerol For PSSD Is HELPING me!!! (Huge potential)

so you don't think it's the result of downregulating 5HT-2A ??
by PsychoGenesis
Tue Nov 10, 2020 5:35 pm
Forum: Treatments and experimentation
Topic: Possible Treatments List
Replies: 44
Views: 65659

Re: Possible Treatments List

I’m also female and just realized that I’ve been suffering from this for so many years. I was on saris for about 7 years. Now I’m on Bio estradiol progesterone and have no libido. Masturbation is too difficult and as a young person I was multiorgasmic. Are there any treatments out there? it's possi...
by PsychoGenesis
Tue Nov 10, 2020 9:02 am
Forum: General
Topic: Questions for people from Russia
Replies: 5
Views: 1499

Re: Questions for people from Russia

This drug isn't seen as effective by many, is compared to homeopathy, and no studies I've seen from from people other than Epstein. Appeared in 2010. Claimed to be of central action and to have no side effects compared to placebo. http://sportwiki.to/%D0%94%D0%B8%D0%B5%D1%82%D1%80%D0%B5%D1%81%D1%81...
by PsychoGenesis
Mon Nov 09, 2020 12:47 pm
Forum: Speculations and hypotheses
Topic: PSSD half a decade later: My brain MRI w/ contrast dye
Replies: 31
Views: 8051

Re: PSSD half a decade later: My brain MRI w/ contrast dye

. The hypo-activity in the frontal lobe that causes the debilitating cognitive symptoms is probably caused by some change in 5HT2A, which is responsible for release of dopamine in the frontal lobe. In PSSD, our receptors get "stuck" in some altered state that is quite different from the n...
by PsychoGenesis
Mon Nov 09, 2020 1:10 am
Forum: Speculations and hypotheses
Topic: PSSD half a decade later: My brain MRI w/ contrast dye
Replies: 31
Views: 8051

Re: PSSD half a decade later: My brain MRI w/ contrast dye

i think if PSSD is indeed a catalyst to something like Alzheimer's then i can't not call it neurotoxic, for these are in and of itself toxic and the behavior of a late stage dementia patient is way worse than many neurotoxins damage, not counting it's sneaky subtlety but i understand both point of v...
by PsychoGenesis
Sun Nov 08, 2020 6:46 pm
Forum: General
Topic: Future directives & endeavors
Replies: 29
Views: 4540

Re: Future directives & endeavors

Hey guys/gals, I'd been absent from the PSSD community for a while. Well, my family and I caught COVID-19 and am currently on the path to recovery. I want to share my ideas with everyone on how to progress on PSSD. I think the most crucial aspect for us as a community right now is gaining awareness...