Search found 81 matches

by Gonzo
Sat Dec 17, 2022 3:05 am
Forum: New Member Intros
Topic: Hello everybody and the effect of loratadine
Replies: 4
Views: 1413

Re: Hello everybody and the effect of loratadine

Yes, loratadine helps, combined with viagra.
Benadryl is actually an SSRI that's why it makes people worse, just like chlorphenamine, both antihistamines.
Loratadine is 100% safe
by Gonzo
Sun Sep 11, 2022 10:03 am
Forum: General
Topic: Post surgery opiods - frustrated as hell
Replies: 1
Views: 619

Re: Post surgery opiods - frustrated as hell

"In vitro studies have investigated the potential mechanisms by which some opioids directly or indirectly increase serotonin levels.6 Dextromethorphan, methadone, pethidine and tramadol inhibit SERT in vitro.7 Fentanyl does not inhibit SERT in vitro but, unlike other opioids, shows affinity for...
by Gonzo
Sun Sep 11, 2022 2:29 am
Forum: General
Topic: Post surgery opiods - frustrated as hell
Replies: 1
Views: 619

Post surgery opiods - frustrated as hell

I'll be having a couple of surgeries soon and I'm basically worried about the post surgery opioids (and abour the antimietic drugs post general anesthesia as I have bad reaction to general anesthesia) I've just read that most opioids acts by inhibiting serotonin reuptake. What should I do? Should I ...
by Gonzo
Tue Aug 30, 2022 5:18 pm
Forum: Treatments and experimentation
Topic: Doxepin?
Replies: 0
Views: 686

Doxepin?

I was prescribed this drug to help with anxiety and allergy at the same time. It's says it is serotonin blocker, 5ht2a and 5ht2c antagonist but also serotonin–norepinephrine reuptake inhibitor (SNRI) (a reuptake inhibitor of serotonin and norepinephrine), but there's no info about tje receptors so I...
by Gonzo
Sun Aug 28, 2022 8:13 pm
Forum: Treatments and experimentation
Topic: Trazodone
Replies: 30
Views: 5842

Re: Trazodone

Most of my profound gains were due to trazodone- increased sensitivity, reduced numbness, increased ejaculate volume, restoration of emotions, ability to feel love, etc. Its also quite risky, I would expect it can cause bad crashes as well. Not surprising because its highly selective for 5ht2a whic...
by Gonzo
Sun Aug 28, 2022 5:40 pm
Forum: General
Topic: Safe anthistamines for PSSD? I would appreciate your experiences..
Replies: 2
Views: 568

Re: Safe anthistamines for PSSD? I would appreciate your experiences..

Hey Gonzo How about loratadine? It's used for allergies but has also been used as an adjunct to reduce ssri side effects. It can also increase the effectiveness of sildenafil (there are threads mentioning this elsewhere on the forum - I've tried it and it increased effectiveness for me.) https://ww...
by Gonzo
Sat Aug 27, 2022 7:06 pm
Forum: General
Topic: Safe anthistamines for PSSD? I would appreciate your experiences..
Replies: 2
Views: 568

Safe anthistamines for PSSD? I would appreciate your experiences..

I've been researching anthistamines as I need more options for a severe chronic condiron. I'm suffering heavily because of this conditon, which is making my life completely miserable, a lot of nights I can't even sleep, but I'm very scared to crash again I'm currently taking Claritin ocassiionally b...
by Gonzo
Fri Aug 26, 2022 6:05 am
Forum: Treatments and experimentation
Topic: Trazodone
Replies: 30
Views: 5842

Re: Trazodone

Most of my profound gains were due to trazodone- increased sensitivity, reduced numbness, increased ejaculate volume, restoration of emotions, ability to feel love, etc. Its also quite risky, I would expect it can cause bad crashes as well. Not surprising because its highly selective for 5ht2a whic...
by Gonzo
Thu Aug 25, 2022 6:19 pm
Forum: General
Topic: Has anyone taken Zyrtec (cetirizine) or Xyzal (Levocetirizine)?
Replies: 3
Views: 475

Re: Has anyone taken Zyrtec (cetirizine) or Xyzal (Levocetirizine)?

https://link.springer.com/article/10.10 ... 21-88982-5
A 57-year-old woman developed serotonin syndrome during treatment with levocetirizine for hives. The woman, who had a history of ...

I can't access the whole study! 😡
Does it seems scary?
by Gonzo
Thu Aug 25, 2022 5:35 pm
Forum: General
Topic: Foods containing serotonergic herbs? Can it make you crash?
Replies: 8
Views: 748

Re: Foods containing serotonergic herbs? Can it make you crash?

Around 2017, my girlfriend gave me some 100% natural herb melissa, in a jar. I took a lot of it, many days (the whole jar actually within some months), a teaspoon in every dose and it didn't affect me at all! (I have pssd since 2003) Then, years later, I was looking for some Melissa again so I tried...