RIP AnhedonicApe, you were definitely one of the nicest, most like able, generally knowledgeable people around. Will really miss you. You put a big effort into doing what you could to recover. I hope people who knew you had at least a little sense of how much you went through prior to needing to sto...

He was one of the nicest guys around. I hope he had had the opportunity to do some of the bigger things he had wanted to in life and that his later days were spent with people able to believe that what he was going through was because of a medication rather than some intrinsic failing. If people had...

I know virtually nothing about Dr. Goldstein, but asked my endocrinologist about him last year, here in New Zealand. He told me that he's had a long and respected career, but as he's aged he's lost a lot of respect in his field for losing sight of science and operating on untested (or badly tested)...

Hi SecondChance, I’m really sad to read what you are going through and can relate because I go through most of it myself. All I can say right now is that over time things get temporarily better and I’m able to just be absorbed in other things to enough of an extent that I forget about my PAS. I thin...

I would give your body at least a month to come back to equilibrium after any medication. However, I can tell you that I think taking Buproprion after SSRIs is basically a bad idea. The solution isn’t more drugs. I took it myself and it made me retarded with no benefits. I have to write papers in my...

This isn’t going to be anything you don’t already know, but I really wouldn’t think about PSSD right now. You probably don’t have it. Why? Because mist people who take SSRIs don’t get it. You are in a crushing life situation right now where you have lost all the sources of love that people rely on f...

Why would Anavar be useful for PSSD (or PFS or PAS)??

My best experience with dopamine drugs was with Modafanil. Ritalin gives me terrible anxiety and is too much of a general rollercoaster. Selegiline gives me chest pain and insomnia. Modafinil made me sharper and more cheerful without any real sides.

Thank you for this explanation. So let’s say the issue is that these drugs imposed epigenetic modifications upon us. What do we need to do to reverse them? Is there any way to ascertain what the modifications were and remediate them in any kind of targeted fashion?

Hi Flowergal, just curious what the outcome of your treatment was. Best regards.