So, because there is no solution involving people taking a variety of supplements / drugs to hit / block certain receptors, this can’t be the answer? This speaks exactly to the issue on this forum and survivingantidepressants and Reddit. Instead of searching for an understanding by practicing medici...

The problem here is that it's very hard to get testing done for SFN. I likely had SFN for the last 10 years (no relationship with my mild to moderate PSSD) and I have only been able to get an appointment for testing in the next few days. I have been denied by 3 other clinics, because knowledge on S...

Agmatine is used to alleviate pain. This would not help regenerate any fibers and hence would not improve symptoms of sexual dysfunction. I really wish people would take the SFP idea more seriously and get the testing done instead of messing around with supplements or pharmaceuticals that target neu...

In no order of importance, here are some SFP exclusive symptoms to look out for. If you have these, you really need to go get a double biopsy and not be worrying about serotonin this or dopamine that or testosterone this. 1. Stinging or prickling sensations all over or especially on the upper legs a...

That’s only to correct an ongoing autoimmune reaction. It’s likely that for most of us, we had an overnight immune surge and woke up with our symptoms. The autoimmune disorder would be gone in that case - only damage left behind.

Not the most common symptom at all. With non-length dependent small fiber neuropathy, most common symptom is brain fog, as far as I’ve been told.

1. Get the biopsies. If all or most of us show polyneuropathy, this objectively arms us to get recourse from pharm.

2. Get the full autoimmune panel to rule out any active response.

3. Small fibers can regenerate overtime if the underlying cause is alleviated.

I am a sufferer but also fortunate enough to be a family member of a prominent immunologist and neurologist. I have studied my disease for over 2 years now. I am as certain as I can be that this is the cause. These other theories involving persistent upregulation/downregulation of various serotonin ...