Sexual Consequences of Post-SSRI Syndrome (jun 2017)

[anacleta]

https://www.ncbi.nlm.nih.gov/pubmed/28642048
Sex Med Rev. 2017 Jun 19. pii: S2050-0521(17)30046-X. doi: 10.1016/j.sxmr.2017.05.002. [Epub ahead of print]
Sexual Consequences of Post-SSRI Syndrome.

Reisman Y1.
Author information
Abstract
INTRODUCTION:
Sexual dysfunctions are well-known side effects of selective serotonin reuptake inhibitor (SSRI) use. Altered libido, erectile dysfunction, vaginal dryness, ejaculatory disorders, and orgasmic problems are frequently reported by patients treated with SSRIs. Moreover, these antidepressant-emergent sexual dysfunctions do not always resolve after discontinuation of the medication and can persist indefinitely. These complaints are termed post-SSRI sexual dysfunctions (PSSD).
AIM:
To examine the existence of this clinical entity, possible theoretical mechanisms, possible risk factors, and possible treatment modalities.
METHODS:
Through literature research and clinical experience, the available information about PSSD is reviewed.
MAIN OUTCOME MEASURES:
Summary of the current literature with insights into possible causes and management options.
RESULTS:
There are some indications that antidepressant-emergent sexual dysfunctions do not always resolve after discontinuation of the medication and can persist indefinitely in some individuals. Although some or all sexual side effects that start with the use of SSRIs might continue after stopping the medication, other sexual complaints can develop. Decreased capacity to experience sexual pleasure is the most frequent characteristic of this syndrome.
CONCLUSION:
The research and understanding of PSSD remain limited and not well understood; however, the data support the existence of PSSD, which can have a substantial effect on the quality of life of these patients. More research is warranted to show the cause and possible mechanisms of PSSD that could lead to the correct diagnosis and treatment. Reisman Y. Sexual Consequences of Post-SSRI Syndrome. Sex Med Rev 2017;X:XXX-XXX.
Copyright © 2017 International Society for Sexual Medicine. Published by Elsevier Inc. All rights reserved.

[Bigmum]

Heh so someone is interested i it

[Glitch]

Wow, this is interesting! I have a feeling that more people are going to start speaking out about this and then more studies are bound to happen.

[future-recovery]

Thank you anacleta. I did not expect this. Finally an author that uses the term Post-SSRI syndrome.

[future-recovery]

I have read it and the review does not seem to be very good in my opinion. Better than nothing and there are a few good sentences, but as a whole it might be one of the most irrelevant PSSD papers I have read. There is nearly no content and there are some questionable statements as well as some statements that either lack sources or have wrong/rather misleading sources. There is even at least 1 wrong(!) statement.
In my opinion one could have written a much much better review.

[anacleta]

Is right, this new article is poor in new content.
But again highlights the pssd and scarcity of research on it.
Can this be a cue for doctors to write articles on pssd, for online newspapers?
If you know some doctor who believes in pssd and can write an article for online newspapers, ask them for a request.


sorry for english

[Maldoror]

Whole paper, anyone?

[anacleta]

Here
https://ufile.io/cj9vj

[GIXXER]

Lets contact them

http://www.issm.info/

[future-recovery]

Here are some mistakes:

1.

The issue of persistent sexual side effects after discontinuation
of SSRIs was first introduced into the medical literature in 2006 by Bahrick

Not completely correct due to this case study: https://www.researchgate.net/profile/Da ... drawal.pdf

2.

the duration of treatment with SSRIs varied from a few weeks to a few years.

Not true, Ben-Sheetrit as well as Hogan reported about cases that had a treatment duration of only a few days.

3.
Table 1: Reisman confuses "anhedonia" with "orgasmic anhedonia". The anhedonia cases that Reisman refers to are not about anhedonia, but orgasmic anhedonia which is the same as pleasureless orgasm which Reisman lists as OD = orgasmic disorder. So it does not make sense to have 2 categories for the same symptom. Moreover emotional blunting (Hogan, Stinson) can occur, but Reisman does not mention emotional blunting, which is not the same as anhedonia by the way.

4.

Management of PSSD has focused on manipulation of the serotonergic and dopaminergic systems

The references are not related to PSSD.

5.

the use of naltrexone has been proposed

Lacks a source

6.

Because of the difficulty of discussing sexual dysfunction and doubts by physicians that persistent sexual dysfunction is due to
SSRIs, many with PSSD remain silent. The emotional, social, and sexual implications of PSSD are widespread and often lead to patients feeling alienated from their peers and loved ones

Wrong reference (not Lareb), it might be Stinson.


Maybe there are even more mistakes.