Crazy results on new combo

[alteredhomeostasis]

Hi all,

I posted on Reddit but if you’re not on there I wanted to share.

Started taking 10mg of Prozac a month or so ago and saw some good improvement. Then I started eating pramipexole here and there (for bodybuilding) and suddenly my libido rocketed. I’m masturbating 2-3x a day and it’s great every time. The ejaculate , rather than dribbling out all thickly, is now coming out like it’s being shot out of a cannon.

This is day 10 I think, and no signs of it wearing off.

Hoping it continues

[Determined-Mind]

Thank you, several people have indeed improved with pramipexole.

How many mg are you taking?

Do you suffer from sensory anhedonia? Either, no pleasure on the body, sex and / or taste pleasure.

What were your symptoms from 0 to 10 before this mixture?

Then now with this mixture ?

Example

Before -----> after

0 ----------> 8/10 for libido
2 ----------> 4/10 for penile pleasure

[alteredhomeostasis]

I’m taking like .1 or .15mg 3-4 times a day. Not really any regimen. I sort of start to feel horny within like 30-40 minutes of taking it.

With no drugs I’m like, 3/10 sexually.
With Prozac maybe I’m 5/10.
With Prozac and Prami I’d say I’m 9/10?

[Determined-Mind]

Great improvements!

Were you suffering from a loss of hedonic sensations (consummatory anhedonia - sexual pleasure)?

Or was your problem mainly a lack of libido (anticipatory anhedonia)?

The neurological circuits involved in the different subtypes of sexual function are not the same.

It would be interesting to know on which pathway prozac vs pramipexole can act on the different symptoms.

[alteredhomeostasis]

Oh, yeah masturbating was often a garbage experience. My pssd symptoms are mainly lack of desire, enjoyment, and shitty unreliable erections. I had really bad PE for a while but that’s improved over time. Shits working great right now

[Determined-Mind]

Enjoy it ^^

[Jaxx]

wow, good to hear this combo works for you!. Think you tried trintellix in the last year, did you recover from it after discontinuation?
I always assumed the buspar-prozac combo worked by balancing pre and post 5ht1a activation, so kinda surprised this works as well. Would love to hear back if it sticks, as desensitization takes a bit longer

[Llonyddwch]

Be very careful with compulsive and addictive behaviors while taking pramipexole.
Good luck! Thanks for sharing