Bupropion May have worsened me

[Fred]

I took Bupropion for a week and saw big improvements in erections and libido but discontinued because of the sides. I have been off for 2 weeks and noticed weaker erections and I feel less aroused from porn. Is this even possible? I’m really scared I might have worsened it!!!

[vkn1]

I would give your body at least a month to come back to equilibrium after any medication. However, I can tell you that I think taking Buproprion after SSRIs is basically a bad idea. The solution isn’t more drugs. I took it myself and it made me retarded with no benefits. I have to write papers in my profession and it severely impaired my ability to write. It has strong anti-cholinergic properties and I have never met someone that actually liked it. Yet people constantly hold out hope for it because it’s marketed as an AD that doesn’t cause sexual dysfunction. As I say, Ive never met someone who is happy with it at all or that experienced sexual benefits from it.

[Numby]

There are several people on this forum who‘ve had positive effects on Bupropion!

[Markc1113]

I took it for a month and it helped with libido and erection majorly. Even for a month after I stopped it.

[Extremaduro]

I crashed with it after 2 weeks with 75mg.

[Markc1113]

75mg is pretty low and I was on the extended release

[Extremaduro]

Yeah low dose. During those 2 weeks I was extremely productive. But abnormally. Had an urge to move and do something. I wasn't able to sit still. Then crashed. What's left for me are tinnitus, anhedonia and dead penis which cannot respond to erectile meds.

[Markc1113]

Yeah that’s scary. I didn’t have that, it helped, continued to help for a month after quitting then went back to baseline of not working

[Markc1113]

Extreme did you ever improve after stopping? I took one bupropion 150mg Wednesday as it helped last time I took it.. it has made me completely impotent for the past two days now and should be out of my system..

[arahant]

It is a type of antidepressant that does not work on SERT.

It is indicated for depressed patients because it is a norepinephrine-dopamine reuptake inhibitor, and takes a few weeks to kick in. So, it can make them more aroused.

But, lots of anxiety can cause SD/ED, which is related to high levels of norepinephrine and epinephrine, which is an extremely aroused state.

If you are experiencing anxiety, taking a drug that increases levels of norepinephrine, may cause constriction of blood vessels.
Then, it might be hard to get erections with constricted vessels.

That is the reason sometimes taking PDE5 does not work every time...Sometimes norepinephrine/epinephrine wins the war on the body's battlefield .