Mirtazapine
Re: Mirtazapine
Not saying you should go back on mirta, but as said the sedation is normal for 2 weeks but will decrease. Up to you if going back to an ssri is a better option, both has risks imo
Re: Mirtazapine
I am quite surprised that so few people on this forum tried mirtazapine.sovietxrobot wrote: ↑Thu Jun 11, 2020 11:59 am Mirtazapine, trazodone, or something similar should be a first-line treatment for PSSD. Sexual side effects from SSRIs are mostly linked to 5HT2 and possibly 5HT3.
Its action is exactly what people believing in the "desensitization theory" would be looking for (directly by HT2A/C antagonism, indirectly on 5HT1 without increasing 5HT level!), in order to relieve symptoms (not to re-sensitize whatever).
There are some crash reports but:
1) Not that many and we have crash reports about everything!
2) I haven't see any scientific proof against it (but I haven't read everything )
I did have some improvement of my slight PSSD with it (low dose: 7,5mg/day) before switching back to escitalopram. I am considering a trial if I don't improve in some months. Any advice / scientific feedback?
Escitalopram, 10mg/day, Jan-May 2019. Fluoxetine, May-Sept 2019. Mirtazapine 7,5mg/day, November 2019-January 2020. Escitalopram, 5mg/day, Feb-May 2020.
Symptoms: sexual & emotional numbness
Symptoms: sexual & emotional numbness
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Re: Mirtazapine
I have tried both in concert. Mirtazipine at 30mg gave me a modest benefit at first, but didnt have much lasting effect. I'm tapering off now because its made me put on a lot of weight. Trazodone has been pretty successful. Interestingly, I see a lot of benefits in the tapering period, even more so than at the initial dose.Thomas wrote: ↑Mon Feb 08, 2021 12:36 pmI am quite surprised that so few people on this forum tried mirtazapine.sovietxrobot wrote: ↑Thu Jun 11, 2020 11:59 am Mirtazapine, trazodone, or something similar should be a first-line treatment for PSSD. Sexual side effects from SSRIs are mostly linked to 5HT2 and possibly 5HT3.
Its action is exactly what people believing in the "desensitization theory" would be looking for (directly by HT2A/C antagonism, indirectly on 5HT1 without increasing 5HT level!), in order to relieve symptoms (not to re-sensitize whatever).
There are some crash reports but:
1) Not that many and we have crash reports about everything!
2) I haven't see any scientific proof against it (but I haven't read everything )
I did have some improvement of my slight PSSD with it (low dose: 7,5mg/day) before switching back to escitalopram. I am considering a trial if I don't improve in some months. Any advice / scientific feedback?
Re: Mirtazapine
Didnt you have muted orgasm after trazodone?
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