PSSD Forum

Corticosteroids are a class of steroid hormones that are produced in the adrenal cortex of vertebrates, as well as the synthetic analogues of these hormones. Two main classes of corticosteroids, glucocorticoids and mineralocorticoids, are involved in a wide range of physiological processes, including stress response, immune response, and regulation of inflammation, carbohydrate metabolism, protein catabolism, blood electrolyte levels, and behavior.

Kk88 wrote: ↑Thu Dec 24, 2020 5:58 am interestingly I also had a recovery when taking naproxen for severe back pain -also an anti inflammatory. May not be linked but sounds like it could be. Really want to try and get some more - obviously not a long term solution but nice for every now and then

Cooperr wrote: ↑Thu Dec 24, 2020 5:11 pm Hello man, may i ask the following questions:

- Erection girth/ length
- Mental arousal/libido
- Erection hardness (Both the penis itself and the pc muscles which start below the testicles, in between your legs. Those muscles should feel almost like contracted metal strings supporting the erection stiffness down below when aroused before PSSD.)
- Morning woods
- Penile scar tissue development or peyronie's like issues/ hourglass shape flaccid or erect.
- Orgasm sensitivity and intensity (controlled by Prostate and pc muscles/nerves)
- Semen volume
- General penile and perineum sensivity (For example, i don't feel my urine coming out, or i don't feel any good while urinating. Before when i was healthy, i would shake my legs while holding a pee and my whole lower body would feel it. Even urinating was amazing. Now thats a faded memory. I am asking this because i am afraid of irreversible nerve damage. Did you remember the warm and sensitive feeling and satisfaction after a pee when you recovered? Do you remember correctly before pssd?)


Did all of these things reversed back to 100- 110% for you when you had that recovery? Can you remember the sensations and sensivity correctly post and pre-pssd?

Thanks. I hope you will recover for good. I hope you can get back at me, i need some hope.

Cooperr wrote: ↑Thu Dec 24, 2020 5:34 pm

Kk88 wrote: ↑Thu Dec 24, 2020 5:58 am interestingly I also had a recovery when taking naproxen for severe back pain -also an anti inflammatory. May not be linked but sounds like it could be. Really want to try and get some more - obviously not a long term solution but nice for every now and then

Can you please read my message above and contribute about your own recovery too thanks a lot guys.

ErgogenicHealth wrote: ↑Sat Dec 26, 2020 2:53 am Finally... some discussion around cortisol/corticosteroids.

Firstly: Low cortisol will lead to LOW dopamine symptoms, and complete emotional BLUNTING.

See this article by my friend:

Thyroid sets the idle for your system, cortisol is your gas pedal. Getting these two right/wrong, will have life-changing consequences.

"Greater motivation and enthusiasm to do things. Both the locus coeruleus (noradrenaline) and the ventral tegmentum (dopamine) are very rich in cortisol receptors. In fact, cortisol drastically elevates dopamine (much more than testosterone). Cortisol also strongly elevates noradrenaline and in high doses, it decreases serotonin. Thus high levels of cortisol make us driven (dopamine), alert (noradrenaline), rigid and obsessive and stressed (decrease in serotonin)¹."

https://thingsvarious.medium.com/cortis ... 3ba8af54e8