OLEAMIDE - Worth Trying?

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ErgogenicHealth
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OLEAMIDE - Worth Trying?

Unread post by ErgogenicHealth »

Studies have shown serotoninergic effects of Oleamide. It makes the 5-HT2A serotonin receptors more sensitive without necessarily influencing the normal signaling process. It also seems to extend the enhanced sensitivity to 5-HT1A and 5-HT2C receptors with no effect on the 5-HT3 receptors and has no effect on serotonin binding to the 5-HT receptors.

Interestingly, Oleamide binds to the 5HT7 receptors and acts as an inhibitor on the 5-HT7 receptor. It acts as agonist on the receptor when no serotonin is present and produces serotonin like effects at a lower intensity.

https://onlinelibrary.wiley.com/doi/pdf ... .0722370.x
Sb919
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Re: OLEAMIDE - Worth Trying?

Unread post by Sb919 »

I was considering it, mostly to help with deep sleep. Apparently it is a CB1 agonist though, which made me reconsider. Not sure how it compares to THC, but I crashed hard after quitting weed at the beginning of the year. Didn't want to ruin any potential recovery I've made in the past 5 months.

https://pubmed.ncbi.nlm.nih.gov/14707029/
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AdvencedResearchPL
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Re: OLEAMIDE - Worth Trying?

Unread post by AdvencedResearchPL »

I tried oleamide at a dose of about 250 mg. It only gave dreams and some anti-inflammatory properties.
ryjoseph97
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Re: OLEAMIDE - Worth Trying?

Unread post by ryjoseph97 »

AdvencedResearchPL wrote: Sat Jul 31, 2021 10:20 pm I tried oleamide at a dose of about 250 mg. It only gave dreams and some anti-inflammatory properties.
How long did you try it for?
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