PSSD weeks after Brintellix/Mianserin

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Eric2021
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Joined: Wed Mar 24, 2021 8:39 am
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PSSD weeks after Brintellix/Mianserin

Unread post by Eric2021 »

1- What is your gender?

Male, 38

2- Why did you take antidepressants in the first place? and for how long were you on them? which med?
Chronic insomnia, mild anxiety
I took Brintellix for 3 months and Mianserin 4 months.

3- How was your sexual and emotional function before antidepressant intake?

Very good, hard erections, I enjoyed sex a lot

4- What are your symptoms exactly and when did they start? sexual dyfunction alone, or cognitive/emotional/hedonistic as well? which symptom is bothering you the most?

Strong ED (no morning woods), genital numbness, reduced orgasms, no libido.

I had some symptoms while on Brintellix but was 90% back to normal after discontinuation. I continued taking Mianserin for 1 month. 2 weeks after quitting Mianserin (6 weeks after Brintellix discontinuation), the symptoms suddenly happened. It got worse in a few days, then some short windows with moderate improvements (few morning woods, orgasm pretty ok, but with a very weak erection). In the last 2 weeks, it worsened. Now ED is total, numbness is very high. Now 2 months with PSSD.

5- What meds/suppplements have you tried so far?
L-Citrulline, ginseng, zinc
Testogel
Cialis

6- Do you have access to meds without prescription (buy online), or would strictly require a prescription for meds to try?
Prescription

7- Can you tolerate galicky foods? what about proteins?

Yes


8- Have you done any blood testing? what were the results?

Pretty normal except for slightly high sugar, low testosterone (but in the normal range)
Eric2021
Posts: 6
Joined: Wed Mar 24, 2021 8:39 am
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Re: PSSD weeks after Brintellix/Mianserin

Unread post by Eric2021 »

Anybody else got their PSSD weeks after discontinuation?
Thomas
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Re: PSSD weeks after Brintellix/Mianserin

Unread post by Thomas »

For many of us (half? I would say) symptoms appeared / increased after discontinuation. Typically one month afterwards.
Escitalopram, 10mg/day, Jan-May 2019. Fluoxetine, May-Sept 2019. Mirtazapine 7,5mg/day, November 2019-January 2020. Escitalopram, 5mg/day, Feb-May 2020.
Symptoms: sexual & emotional numbness
Eric2021
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Joined: Wed Mar 24, 2021 8:39 am
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Re: PSSD weeks after Brintellix/Mianserin

Unread post by Eric2021 »

Ok, I thought most had their symptoms shortly after discontinuation. I felt my case was strange because I had an almost total recovery one or two days after discontinuation. The new, severe symptoms (different from those that I had on the meds) appeared weeks after discontinuation.
ytho
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Joined: Mon Mar 15, 2021 11:07 am
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Re: PSSD weeks after Brintellix/Mianserin

Unread post by ytho »

My symptoms appeared only very few days after discontinuation of the medication. I did not have any symptoms while on the medication.

May I ask how you would describe the genital numbness? I'm having a hard time figuring out if thats the case for me as well, since its not really written anywhere how that feels.
Eric2021
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Joined: Wed Mar 24, 2021 8:39 am
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Re: PSSD weeks after Brintellix/Mianserin

Unread post by Eric2021 »

In my case, there are 2 aspects: mechanical numbness and sexual numbness. The mechanical numbness means I feel almost nothing while touching it like when your mouth is anesthesized at the dentist. I could pinch my penis very strong without feeling any pain. This aspect has improved recently though.
Sexual numbness means I don't feel anything sexual, no matter how hard I try, it's the same as touching my arm or my leg. This aspect has recently worsened.
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