kpavel wrote: ↑Mon May 11, 2020 3:27 am
cdraham wrote: ↑Sun May 10, 2020 6:32 pm
Very interesting indeed, may I ask what your symptoms before were? How was your reaction to alcohol, recreational drugs?
What exactly did you do to help your mitochondria? Do you feel 100% cured of your PSSD now?
btw: the member helvy improved on HBOT initially before his crash, that might have boosted mitochondria function
I did some research and came across 10 pass ozone therapy, something I might try.
Yes, really, I feel like a cured man, it was something very notable happening and things are still improving. First of all it is a feeling that obstacles in life is not something to worry about. I stopped doubting a lot, sort of an alpha-male (yes, I can, it's not difficult) feeling inside (so it's only partly about testosterone, more about dopamine). Also you know, when you suspect a heart condition life becomes very miserable. Now I can do things till 1 am every day if I want.
Another symptom is I began sweating normal and I'm less restless. I had very little sweat, my sleep was intermittent, I didn't feel a pleasure to sleep a little more. Also my hands were in increased tonus/tension state, especially veins were very prominent on them several times in a day. When I walked my heart rate was more than 100 bpm, and when I stopped it didn't calm for a long time, so called intolerance to exercise, I guess. So this all was a lot of discomfort, stopping any pleasure in life. Also I can read texts on screen and not return to repeat, like I did in the worst times, but see the whole picture from page.
Interesting fact, I began playing computer games a lot, it's not a meh now. I feel it is easier to become an addict now). I drink coffee more than ever. Watching dreams every night
, they are colorful, sometimes erotic, I can be almost woken up and continue dreaming if you understand what it feels like. My morning erections are everyday. I also noticed my balls have grown. Strange coincidence. Also my laughing is more spontaneous and natural.
I don't use drugs, it's not legal here and really dangerous. Not worth it. I react to wine well, increased mood, even more than from caffeine-containing drinks.
I combine several supplements everyday, but believe the most useful were niacinamide, d-ribose, lecithin, resveratrol and carnitine. Probably PQQ, but not now, 2 years ago my connecton feeling from brain to penis was restored while taking pqq.
Oxygen/ozone can be helpful for mitochondrias but obviously in the right concentration.
https://www.ncbi.nlm.nih.gov/pubmed/25828268
https://www.ncbi.nlm.nih.gov/pubmed/31827546
https://www.ncbi.nlm.nih.gov/pubmed/25701186
https://www.ncbi.nlm.nih.gov/pubmed/29022413
Declining NAD+ Induces a Pseudohypoxic State Disrupting Nuclear-Mitochondrial Communication during Aging
https://www.cell.com/cell/fulltext/S009 ... 13)01521-3
Ever since eukaryotes subsumed the bacterial ancestor of mitochondria, the nuclear and mitochondrial genomes have had to closely coordinate their activities, as each encode different subunits of the oxidative phosphorylation (OXPHOS) system. Mitochondrial dysfunction is a hallmark of aging, but its causes are debated. We show that, during aging, there is a specific loss of mitochondrial, but not nuclear, encoded OXPHOS subunits. We trace the cause to an alternate PGC-1α/β-independent pathway of nuclear-mitochondrial communication that is induced by a
decline in nuclear NAD+ and the accumulation of HIF-1α under normoxic conditions, with parallels to Warburg reprogramming. Deleting SIRT1 accelerates this process, whereas raising NAD+ levels in old mice restores mitochondrial function to that of a young mouse in a SIRT1-dependent manner. Thus, a pseudohypoxic state that disrupts PGC-1α/β-independent nuclear-mitochondrial communication contributes to the decline in mitochondrial function with age, a process that is apparently reversible.