the drug that cured long-covid individuals (BC 007)

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MisterCharlie
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Re: the drug that cured long-covid individuals (BC 007)

Unread post by MisterCharlie »

nicopickle wrote: Wed Dec 15, 2021 11:18 pm
I will leave a link below on the article about the drug eliminating peoples symptoms in a matter of hours,

https://t.co/i7zSsGTu2B
English version?
nicopickle
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Re: the drug that cured long-covid individuals (BC 007)

Unread post by nicopickle »

MisterCharlie wrote: Thu Dec 16, 2021 5:30 pm
nicopickle wrote: Wed Dec 15, 2021 11:18 pm
I will leave a link below on the article about the drug eliminating peoples symptoms in a matter of hours,

https://t.co/i7zSsGTu2B
English version?

Hope for millions of people affected
German doctor cures Long Covid for the first time: "It's like a giant miracle"

Germany, doctors have achieved a breakthrough in the treatment of long-covid patients for the first time
FOCUS online editor Corinna Schneider
Monday, 09/27/2021, 6:33 am
At the Eye Clinic in Erlangen, doctors have achieved something that has never been done before: four Long Covid patients were cured by giving them a cardiac drug that was not yet approved. FOCUS Online spoke to one of the treating doctors about the medical surprise success.

Fatigue, exhaustion, breathing difficulties, brain fog, odor and taste disorders as well as depressive moods. These are just a few of the many symptoms that those affected by corona can still suffer months after their infection. For many, these long covid symptoms are so severe that they can neither work nor cope with their everyday lives on their own.

The sad thing about it: To date, there is no cure - at most, individual symptoms such as pain can be alleviated with medication or therapy. Corona ambulances all over Germany are therefore trying to help thousands of Long-Covid victims as best they can.

Brain fog subsided just a few hours after the drug was administered
But there has been hope since July. Because doctors at the eye clinic at the University Clinic Erlangen have succeeded for the first time in curing four people, some of whom were severely affected by Long-Covid, by administering the active ingredient BC 007, which was originally developed as a heart drug. "It was like a giant miracle when we noticed that the patients were symptom-free," explains the ophthalmologist and molecular medicine specialist Bettina Hohberger to FOCUS Online.

Although healing does not occur immediately, but gradually over several weeks, all four patients noticed a clear improvement relatively quickly. "In some cases, for example, the brain fog subsided just a few hours after the infusion - so that the patients could think clearly again," explains the doctor.

Eye check for corona patients in the intensive care unit
The fact that such a breakthrough in the treatment of Long Covid patients has now been achieved in an eye clinic of all places has a specific reason: “We have been researching glaucoma for years and know that so-called autoantibodies play a role in this eye disease - they have an influence on the intraocular pressure and impair the blood circulation in the eye, ”says Hohberger.

"We were just preparing to use neutralizing drugs against these autoantibodies in the treatment of glaucoma patients when the pandemic began," explains the doctor. For this approach, Hohberger was even nominated last year for the "Galenus-von-Pergamon" science award in the basic research category.


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Since she regularly looks after the intensive care units at the University Clinic Erlangen, she has also examined the eyes of Covid patients since the beginning of the pandemic. “Physical changes can be seen in the eye very early, so that systemic intensive care therapies can be adapted accordingly. That is why it has been the medical standard for decades to regularly check the eyes of intensive care patients, ”explains Hohberger.

Eye blood flow disturbed in former corona patients
"With a senior physician in the intensive care unit, we came to the assumption that the blood circulation in the eye could change as a result of a corona infection, since the virus itself can attack the innermost layer of the finest blood vessels," continues Hohberger. This then resulted in the so-called " ReCOVer " study, in which Hohberger and her colleagues specifically examined the eyes of former corona infected people in order to observe long-term effects.

With the help of so-called OCT angiography, a non-invasive imaging method, the doctors were actually able to determine that even months after an infection with Sars-CoV-2, the blood circulation in the retina was significantly restricted in many patients.

Autoantibodies detected in the blood of former corona patients
When the interdisciplinary science team in Erlangen, together with a long-term cooperation partner in Berlin , also detected autoantibodies in the blood of these former infected people, another suitable piece of the puzzle was found. “We knew exactly these autoantibodies from our glaucoma patients,” explains the doctor.

"Since autoantibodies can attack not only the blood vessels in the retina, but possibly also in other parts of the body, the assumption was made that the drug that we originally wanted to use in our glaucoma patients could also help with long-covid symptoms." she continues.

First attempt at healing a glaucoma patient with Long-Covid
When a 59-year-old glaucoma patient reported his Long Covid complaints after the corona infection in the Erlangen clinic, the doctors offered him an individual healing attempt. "We administered BC 007 to him as a single infusion and observed him on the ward for three days." The patient already felt better during his inpatient stay. As a result of the treatment, his ability to concentrate and his sense of taste also returned.

Hohberger and her colleagues were also able to objectively determine an improved blood flow in the eye and a decrease in autoantibodies. "We were astonished that the patient was completely symptom-free thanks to the improved blood circulation," says Hohberger looking back.

More about Long Covid
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Head of the clinic on the Long Covid phenomenon:
Rehabilitation doctor on increasingly younger Long Covid patients: "I have crying parents on the phone"
Relief of symptoms also in the case of tremors and symptoms of paralysis
The second patient, who heard of the healing and contacted the clinic, also healed quickly. The 51-year-old Oliver G. has been severely physically restricted and no longer able to work since his corona infection, which was more than a year ago at the time of treatment at the end of July.

Reading tip: "There is an end to vegetating" - Long-Covid makes Oliver a "zombie" - until cardiac medication heals long-term effects after just one day
As a result of the drug, not only did his brain fog disappear within 24 hours, but the severe tremors in his right hand and arm from which he was suffering also stopped on the second day after treatment. Within the first week, the sense of balance, coordination and memory performance improved - the states of exhaustion also became weaker. He is now symptom-free and can work again.

The same thing was repeated in the meantime in two other Long Covid patients, including a 39-year-old primary school teacher who suffered from paralysis and was partially dependent on a wheelchair. Her condition has also improved continuously since she was given the medication.

No side effects and complications so far
Since these healing successes, Hohberger and her colleagues can hardly save themselves from inquiries. "We receive hundreds of letters from people who are looking for help - including ME / CFS patients (myalgic encephalomyelitis / chronic fatigue syndrome) who have heard of it and are hoping for a cure." Help patients more. “The drug has run out, we only had a few doses,” she explains.

Because BC 007 is in the approval phase and is therefore not even available on the market. The fact that it is a heart preparation is of no further importance. "It is part of the regulations that drugs must be approved for a certain disease - since BC 007 eliminates autoantibodies in the blood, it could theoretically be used for glaucoma or even now long-covid in off-label use," said Hohberger. So far, the doctors have not found any negative side effects or complications.

Research application submitted to the Federal Ministry of Education and Research
Therefore, Hohberger and her colleagues want to continue researching the promising drug as soon as possible. "We have submitted an application to the Federal Ministry of Education and Research so that we can carry out a study with this drug on Long Covid patients."

Long-Covid patients who are interested in treatment with the drug as part of a study could contact recover.au@uk-erlangen.de . "We are continuing to screen long-covid patients as part of the ReCover study - we then also select the participants in the drug study from this group," said Hohberger.

Pacing important for long covid patients
As long as there is no approved drug available for healing, Hohberger Long Covid advises those affected by so-called "pacing", which ME / CFS patients are also advised to use. "This is understood to mean the moderate use of your own strength reserves," explains the doctor. It is important that patients do not go beyond their own performance limits. "If someone is overwhelmed and cannot get up for days because of exhaustion, that is certainly not the right way."

Since the blood flow, as Hohberger and her colleagues were able to determine, plays an elementary role, the doctor also advises patients to use their physical reserves to get some fresh air and, for example, go for a walk. "It would be good if the patients exercise regularly without overstraining themselves, so that the blood circulation does not deteriorate further and there is also no muscle breakdown." That would only worsen their condition, the doctor sums up.

After the corona vaccination, many would like to test whether it has worked for them. They have their antibody levels checked. Laboratory doctor chief Andreas Bobrowski explains on FOCUS Online when the value is high enough - and when a third vaccination makes sense. Vaccinated or recovered - do I have enough antibodies? Doctors boss says what value protects you from Covid

"There is an end to vegetating"
Long-Covid turns Oliver into a "zombie" - until cardiac medication heals long-term effects after just one day!
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FindGoodNickname
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Re: the drug that cured long-covid individuals (BC 007)

Unread post by FindGoodNickname »

Thank you for the info! I didn't know that chronic fatigue patients also have a strong interest in this.
nicopickle
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Re: the drug that cured long-covid individuals (BC 007)

Unread post by nicopickle »

FindGoodNickname wrote: Thu Dec 16, 2021 8:17 pm Thank you for the info! I didn't know that chronic fatigue patients also have a strong interest in this.
majority of CFS patients end up with issues after a virus/antibiotics, which seems like a fked up immune response incoming. I believe this is the original issue for most people with these issues. unfortunately I tried to share this info on the pfs forum, but they deleted my posts. if anyone has anyone they care about that mostly stays on the pfs forum, please let them know that there is hope. thats all i wanted to accomplish by my post on there
Jcumbo
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Re: the drug that cured long-covid individuals (BC 007)

Unread post by Jcumbo »

Yeah, I was reading this post on the PFS forum and it was deleted when I was mid way through. They are silly for deleting this. And yes, this is incredibly interesting to say the least.
nicopickle
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Re: the drug that cured long-covid individuals (BC 007)

Unread post by nicopickle »

Jcumbo wrote: Thu Dec 16, 2021 8:53 pm Yeah, I was reading this post on the PFS forum and it was deleted when I was mid way through. They are silly for deleting this. And yes, this is incredibly interesting to say the least.
thank you for that. i was incredibly frustrated with them after that. they even had the audacity to tell me to "read the fucking FAQ"
Jcumbo
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Re: the drug that cured long-covid individuals (BC 007)

Unread post by Jcumbo »

They seem so fixated only on androgens when the whole body is so complex. Just the fact that pssd, PFS, and pas all seem to be related by different drug mechanisms is maybe pointing to something like this being the culprit. Since millions of people are apparently suffering from long COVID this will be addressed
Sooner rather than later. This could be good for the pssd and other communities.
nicopickle
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Re: the drug that cured long-covid individuals (BC 007)

Unread post by nicopickle »

Jcumbo wrote: Thu Dec 16, 2021 9:12 pm They seem so fixated only on androgens when the whole body is so complex. Just the fact that pssd, PFS, and pas all seem to be related by different drug mechanisms is maybe pointing to something like this being the culprit. Since millions of people are apparently suffering from long COVID this will be addressed
Sooner rather than later. This could be good for the pssd and other communities.
agreed. i just hope that if this is the solution. i hope that they wont keep this information from the community over there, they deserve to have this info.
Jcumbo
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Re: the drug that cured long-covid individuals (BC 007)

Unread post by Jcumbo »

Don't worry if it is then there's heaps of people jumping to and fro from Reddit, here, and Propecia help so they'll find out. Although, it would be good if the PFS mods took this seriously as they have a bit of push with research etc. And at least you have tried to let them know so good on you.
bigpoppa10040
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Re: the drug that cured long-covid individuals (BC 007)

Unread post by bigpoppa10040 »

nicopickle wrote: Thu Dec 16, 2021 8:20 pm
FindGoodNickname wrote: Thu Dec 16, 2021 8:17 pm Thank you for the info! I didn't know that chronic fatigue patients also have a strong interest in this.
majority of CFS patients end up with issues after a virus/antibiotics, which seems like a fked up immune response incoming. I believe this is the original issue for most people with these issues. unfortunately I tried to share this info on the pfs forum, but they deleted my posts. if anyone has anyone they care about that mostly stays on the pfs forum, please let them know that there is hope. thats all i wanted to accomplish by my post on there

I’ve been a member there for years...any mention of immune system or autoimmunity is immediately shut down. I appreciate all they’ve done for the community I really do. But it’s just flat out strange and weird. I’ve had top doctors tell me they believe the immune system is the core issue at play. Many many members agree too but when the threads are commented on they are immediately derailed or moved to the bottom....too strange in my opinion. Other users have called this out before too.
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