forexworld12 wrote:I am pretty positive it should work just that it might take 3 to 4 weeks to start working maybe even more since you are on a very low dose and using the patch and i have no idea how would the patch work and if it is able to replicate the rat study.
It did reverse pssd in lost soul by a great extent after 19 days but that patient was not fit for the trial due to his history of hardcore drug abuse
Pretty much this, but also more people will need to try this to get a good understanding of the effectiveness of this. 2 people isn't enough of a trial and I fear this falls to the wayside when it could really help people.
Maybe lost soul can shed more light on his current health so that people aren't scared of trying this.
I can just tell this: "crap".
My lab results are either for laughing or crying -if I could cry but I can't: my estradiol levels are exactly the same as without the patch , 38 (reference range 11 - 44) and I'm now more hypogonadal than I was, testosterone 2.9 (range 1.75 - 7.8). With two weeks, I should have a higher estradiol value by now. This obvioulsy needs a very different approach, but now I fear that I can't absorb it through the skin. If this isn't working I guess I will try injections instead of trying a higher dose patch. Any ideas?
Blackout wrote:I can just tell this: "crap".
My lab results are either for laughing or crying -if I could cry but I can't: my estradiol levels are exactly the same as without the patch , 38 (reference range 11 - 44) and I'm now more hypogonadal than I was, testosterone 2.9 (range 1.75 - 7.8). With two weeks, I should have a higher estradiol value by now. This obvioulsy needs a very different approach, but now I fear that I can't absorb it through the skin. If this isn't working I guess I will try injections instead of trying a higher dose patch. Any ideas?
I told you the truth and you got offended. The way and the dose of e2 you took did exactly what it was supposed to do. It is well known that e2 gives the shutdown signal to the hypothalamus for LH and FSH. That is exactly what happened. No need to get mad now.
Death is not the greatest loss in life. The greatest loss is what dies inside us while we live.
My update is that not even at 100 mcg dose -4 times my initial dose for a week and a half- felt anything other than increased fears all day and night about getting DVT or stroke, or even a worsening of my cognitive functions which it really , really bad since last year, maybe already at the level of MCI -mild cognitive impairment- that is not so mild. And yes, I am on TRT.
I'm currently down to 50 mcg and on TRT.
But I feel lost, really lost. At this time I more desperate to be able to recover my cognitive function, more than my sex drive, because I now fear a lot ending in the streets not knowing who I am, wandering, eating garbage, dressing with whatever I find. While doing all of this estradiol trial, I've been reading many more things, and definitely, the worsening that I got overnight since a year and a half came due to several months of arimidex -since estradiol is also neuroprotective even in men-. I found that I very likely have now PSSD combined with chemo brain -I didn't know about this-, which is a cognitive deterioration that comes while using some anti cancer drugs that deplete or block estradiol -such as arimidex. But on the other hand, I read that estradiol replacement can induce even more memory loss if given after a long time after menopause to women, and since I have been in andropause and since last year estradiol depleted, I guess this is equivalent to be in menopause and that's why I fear becomming a full blown retarded person if estradiol finishes what arimidex began for sure. Oh, and also found that HCG -translated into high LH- can also induce cognitive impairment, and I also used it for the same time lenght that I used arimidex, but in tiny doses as they're supposed to be.
I guess no one is interested in my rambling about my chemo brain and the sort, since what you want is a PSSD answer. I repeat, at 100 mcg I still got nothing -save for general malaise the first day on that dose, including some kind of heat in my skin all over the body. At this time I have slightly bloated ankles -just as I had when injecting testosterone without aromatase inhibitor back in 2012, when I got my only true window in this 6 years of nightmare.
I'm afraid -more-. It has been nearly 5 weeks since I started this, and I just noted a big lump in my right armpit. Can estrogen dependent cancers develop this fast??? Whatever this lump is, it sure has some relationship with what I'm doing.
I was much more terrified of getting thrombosis or stroke, and now I get this. Any insight is welcome, please.
I know this is not a forum about breast cancer, but I'm in panic now. I just found a case report of a man that developed invasive breast cancer just 5 weeks after starting TRT. I'm really desperate -yet I can't cry-. As I stated a couple of days, I intended to remain on TRT from now on even if I stopped estradiol, just because I was already hypogonadal before starting with the patches . If I have to live without both T and E, not only I'm more than doomed with PSSD, but moreover, my cognitive dysfunction that I just attributed to my past year use of arimidex will become far worse. I can't describe what I 'feel' and think now.
If you are worried about this, you should see your doctor. I wish that I could help you determine what this lump is, but I can't. If you are worried about it then see a professional.
- Medical Student & Friendly poltergeist - Lexapro Sept '14. [Hx] [PSSD Lab] [r/PSSD] [Treatment Plan] - Add "Ghost" in replies so I see it
By ultrasound imaging, I have a solid mass in my right breas, a larger, solid and painful mass in my right armpit , and painful and swollen lymph nodes there too. This doesn't look good. And it was just in 5 weeks. The pain has been increasing.
On the other hand, I must say that about two days before discovering the armpit masses and removing the patches, I began having increased ability to sustain an erection -considering that since the past year I lost completely that ability after having had PSsD for 6 years. Just manual erections, but that's it. But two more things. First, my ejaculation got thicker. Too little as usual, but thicker, and... maybe this is a useless sign, but for the first time since 2011, I got oily skin in my face -very oily as it used to be. Testosterone alone didn't produce any of these effects -erection or oily skin- when I tried it twice in these past years. After the patches were removed, even with this increased fear of what I got in my armpit/breast, I managed to get relatively firmer erections and the oily skin remained for I guess a week or two. Then things went down again. Lost soul did mention a recovery of everything except erectile function, and in my case was the opposite. I masturbated several times a day those days, but it was just psychological, not that I really felt the urge to do so.
By the way, I still continue with testosterone but not estradiol -in fact with the arimidex that I despise so much- even when I feel that I have a death sentence from possible cancer. I refuse to live without any sexual hormones if cancer is confirmed. Even with arimidex, my ankles are swollen, despite my estradiol levels already being within range. I have fear. i don't know where I'm going now but I can figure it out.
I really played the role of a Guinea pig with this. I have lots of fear.
Blackout, dude, sorry to hear about the pain and swelling you are experiencing. How big and in what area is the breast swelling? I don't have any medical training but I experienced similar tenderness and lymph node growth in my right armpit and it did not develop into anything serious and has gone away. I really hope you are OK.
21, male, extreme pssd for four years
Tried inositol (slight improvements) cialis (very limited improvements) yohimbine (slight improvements) maca root (no effect) bacopa monieri (no effect) estradiol-17b (pronounced improvement in all areas of sexuality)
