Charles10 - my history and what i've tried

[Charles10]

Hi, i would like to tell a little about me, my fictitious name is Charles, i'm 22 yo, i'm brazilian (i dont speak english so fluent)

my story with the anti depressants starts in 2012 when i took fluoxetine 20mg for depression, i quickly up to 40mg daily, but i didnt see many improvements then i decided to stop... nothing had happened with me about sex... my libido was high ( i was a teenager this time, 16 yo), ... in 2015 i took sertraline 100mg for some months, after i started lexapro.. nothing happened... all ok... until 2016, when i started again to take lexapro... when i stopped lexapro all the symptoms show up and i am this shit until now..

i am on pssd about 3 years, since 2016, the first 6 months i didnt know what i had, i had been thinking in something psicological this time, it was horrible when we dont know what we really have.... i discover i had pssd by this forum because of the similarity with all the symptoms i have.. E.D, low libido, anhedonia, genital anesthesia, lack of emotions etc.

i have gone to many doctors since this time, psychiatrists, urologists and neurologists, but unfortunately no one knows about pssd here, then i decided to try many drugs, the most i had saw here

i'm a medicine student, now on 4° year, then it was not hard to obtain the drugs.

my list of what i've already tried:

- testosterone injections (durateston, masteron)
- Proviron (a testosterone pill)
- oxicitocin (nasal and injetable)
- HCG
- tamoxifen
- clomifen
- anastrozole
- maca root, tribulus terrestris and mucuna pruriens
- desvenlafaxine
- bupropion
- trazodone
- sildenafil / cialis
- D vitamin
- levotiroxin
- cabergoline
- cyproheptadine
- hypericum (SJW)
- pramipexole
- yohimbine
- baclofen
- metergoline
- itraconazole (anti fungi)
- ondansetron (5-HT3 antagonist)
- resveratrol
- metronidazole + probiotics later
- forskolin (with metergoline gave me good improvements)
- pyridostigmine
- teacrine
- levodopa + carbidopa
- EGCG
- codergocrine (hydergine)
- vimpocetine
- agomelatine
- lithium

how you can see, it's a big list, i tried some of these drugs together, my idea was: ''many things have already been tried here, then i will try some combos to see what happen'' , some drugs makes me better, others dont, but no one had a very good result, besides metergoline that i had about 50% improvement in all areas, i want to try again later

but seems how much more drugs i took, worse i was... the most crazy thing i've did were mix 8 drugs and take together all day, i didnt want to know if i would die, i was only so so bad that i just want to try anything, i was not patience because i didnt support... i simple didnt support to live this way anymore... but all the things i tried probably make me worse... my brain is so devastated...

I just want to be what i was before all this, i dont know what to expect in the future but i will be a psychiatrist and try to find a cure for this until the end of my life or until i heal myself

[felipekj]

Hi, i would like to tell a little about me, my fictitious name is Charles, i'm 22 yo, i'm brazilian (i dont speak english so fluent)

my story with the anti depressants starts in 2012 when i took fluoxetine 20mg for depression and social phobia, i quickly up to 40mg daily, but i didnt see many improvements then i decided to stop... nothing had happened with me about sex... my libido was high ( i was a teenager this time, 16 yo), ... in 2015 i took sertraline 100mg for some months, after i started lexapro.. nothing happened... all ok... until 2016, when i started again to take lexapro... when i stopped lexapro all the symptoms show up and i am this shit until now..

i am on pssd about 2 years, since 2016, the first 6 months i didnt know what i had, i had been thinking in something psicological this time, it was horrible when we dont know what we really have.... i discover i had pssd by this forum because of the similarity with all the symptoms i have.. E.D, low libido, anhedonia, genital anesthesia, lack of emotions etc.

i have gone to many doctors since this time, psychiatrists, urologists and neurologists, but unfortunately no one knows about pssd here, then i decided to try many drugs, the most i had saw here

i'm a medicine student, now on third year, then it was not hard to obtain the drugs.

my list of what i've already tried:

- testosterone injections (durateston, stanozolol, masteron)
- Proviron (a testosterone pill)
- desvenlafaxine
- tamoxifen
- clomifen
- Wellbutrin
- sildenafil / cialis
- trazodone
- oxicitocin (nasal and injetable)
- D vitamin
- levotiroxin
- cabergoline
- itraconazole (anti fungi)
- cyproheptadine
- HCG injections
- hypericum (SJW)
- yohimbine
- pramipexole
- maca root, tribulus terrestris and mucuna pruriens
- metergoline
- anastrozole
- ondansetron (5-HT3 antagonist)


how you can see, it's a big list, in a not much time, because i tried some of these drugs together, my idea was: ''many things have already been tried here, then i will try some combos to see what happen'' , some drugs makes me better, others dont, but no one had a very good result

but seems how much more drugs i took, worse i was... the most crazy thing i've did were mix 8 drugs and take together all day, i didnt want to know if i would die, i was only so so bad that i just want to try anything, i was not patience because i didnt support... i simple didnt support to live this way anymore... but all the things i tried probably make me worse... my brain is so devastated...

now i'm a little more resignated , i'm currently taking Trazodone 150mg , Yohimbine 10mg daily. And Tadalafil 20mg when i have sex, at least i can have sex this way, with 3 drugs that help erection it's not so difficult

fortunately i have a girlfriend that understand me and support me with this, but it's not enough, the problem is not only about sex... i just want to be what i was before all this, but i dont know what to expect in the future.

i have been reading this forum for some months, but it's my first post, i wish everyone better one day, thank you

Eae mano, sei como é isso, tenho PSSD a 7 anos, ta foda mas temos que continuar vivendo né, se quiser falar alguma hr só chamar lá...

[Charles10]

hey dude sry ur here
i read u tried everything almost..

since ur a medical student i would like to suggest u to check out HDAC inhibitors

this was suggested by a fellow sufferer from this forum
im currently checking experiences on the PFS forum where there are lots and lots more posts
the PFS and PSSD are almost simmilar with appart from sexual side effects,we both dont respond to alcohol and benzos etc..

HDAC inhibitors that are mentioned and tried by some are
-Valporate
- Sodium butyrate

idk anything about this since i have just started reading about this stuff and this is only my personal suggestion
also my personal opinion is that the current theory about dessentisation posted by the moderators here is wrong and is far from reality for me
im just stating my thought and i hope no one will sanctione me because of this

regards

Valporate is the sodium valproate/valproic acid? A mood stabilizer for bipolar?

The butyrate i unfortunately didnt find here, seems to be a rare drug

[Jaxx]

Hi Charlie welcome to the forum and thanks for the elaborate introduction.
Did you perhaps combined the cyproheptadine with prami/caber? Ive been looking in the combination of this (or similar).
Most hormones indeed didnt seem to do much in most, avanar being one of the few that seems to move the needle, but not a cure yet.

[Charles10]

Hi Charlie welcome to the forum and thanks for the elaborate introduction.
Did you perhaps combined the cyproheptadine with prami/caber? Ive been looking in the combination of this (or similar).
Most hormones indeed didnt seem to do much in most, avanar being one of the few that seems to move the needle, but not a cure yet.

My memory is unfortunately very affected, idk if it is because of the pssd or the drugs, probably both, i dont remember very well but i know that when i was using cypro 16mg/day i took cabergoline too 0.5/week , the pramipexol i took alone for 2 weeks with no effect (first 0.375 after 0.750mg)

I really felt better when i took cabergoline with clomifen (i think it is recommended by dr goldstein, i saw here in the forum), but was only the first day i took

Anavar is oxandrolone right, i dont know about it, but my next try will be dianabol (metandrostenolone) with bupropion, dianabol seems to be good for libido, and reduces a lot the cortisol

[Charles10]

yes that is the product
steven got healed by it
he doesnt come to this forum anymore as u can see
he got valproate and ella one and its now normal
but i suspect he didnt have real pssd
i have to gather further evidence about that subject
we are contacting him via phone so we will see soon
i will report back when i know

i want to try some mood stabilizer like valproate, but i dont know when i will get it, maybe next year, i need a break of drugs in my brain, thanks for the suggestion