Everything we knew about PSSD is wrong. Check out why.

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Jaxx
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Re: Everything we knew about PSSD is wrong. Check out why.

Unread post by Jaxx »

You have made some bold posts in the past, with interesting ideas but very limited practical implications and at a key moment, testing a hypothesis, never reported back.
So my feedback might sound a bit negative; there are plenty of theories around pssd, without clinical proof/ markers etc about the mechanism, it will be of limited use, at least on short term. People here are focused on the practical implications to help their situation. Holding back on posting possible treatments because they might not work for everyone is not a good argument imho, people are continuously jumping on strong steroid regimens, cancer meds because of n=1 reports from reddit boards. Any deeper explanation of a possible cure with some watch-outs seems far less dangerous to me.
arahant
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Re: Everything we knew about PSSD is wrong. Check out why.

Unread post by arahant »

Jaxx wrote: Thu Nov 24, 2022 4:30 pm You have made some bold posts in the past, with interesting ideas but very limited practical implications and at a key moment, testing a hypothesis, never reported back.
So my feedback might sound a bit negative; there are plenty of theories around pssd, without clinical proof/ markers etc about the mechanism, it will be of limited use, at least on short term. People here are focused on the practical implications to help their situation. Holding back on posting possible treatments because they might not work for everyone is not a good argument imho, people are continuously jumping on strong steroid regimens, cancer meds because of n=1 reports from reddit boards. Any deeper explanation of a possible cure with some watch-outs seems far less dangerous to me.

Jaxx,

As you said, it is not new; lot's of theories around, and every once in a while, someone joins this forum with the same behavior:
Believing they have some special knowledge, grandiose claims, talkativeness in walls of texts, and fancy theories that "found" the "etiology/cure" of XYZ.
Types making claims like that are found in every community where people are hopeless about some medical condition. The most common is "I found a cure/etiology of Cancer",

Here's another didactic example of a "specialist" that even ran Q/A sessions during the early ages of this forum:
viewtopic.php?t=4417&hilit=brooks

Curiously, such posts appear in episodes; then disappear after some hype cycle.
What worries me a lot is that many people are desperate and may end up jumping into crazy experiments.
PSSD is tough, and sufferers are not immune to grandiose claims, then some active forum moderation might be needed.

If @guacamo wants to be taken seriously here, he should be more transparent.

Arahant
Wellbutrin (2007 - 2018)
Wellbutrin + Sertraline (2015)
Wellbutrin + Ritalin (2016 - 2018)
Wellbutrin + Ritalin + Sertraline (3 months in 2018)
Buspirone (Feb 2019 - Today)
Ritalin + Buspirone (Nov 2019 - today)
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guacamo
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Re: Everything we knew about PSSD is wrong. Check out why.

Unread post by guacamo »

Jaxx wrote: Thu Nov 24, 2022 4:30 pm You have made some bold posts in the past, with interesting ideas but very limited practical implications and at a key moment, testing a hypothesis, never reported back.
So my feedback might sound a bit negative; there are plenty of theories around pssd, without clinical proof/ markers etc about the mechanism, it will be of limited use, at least on short term. People here are focused on the practical implications to help their situation. Holding back on posting possible treatments because they might not work for everyone is not a good argument imho, people are continuously jumping on strong steroid regimens, cancer meds because of n=1 reports from reddit boards. Any deeper explanation of a possible cure with some watch-outs seems far less dangerous to me.
You have made some good points, I am aware that there are people who will run into most random thing with just 0.001% chance of working, that shows how desperate people are here and I do not blame them. But I do not want to be responsible for motivating other people to do anything of this kind. Future topic might touch on supplements that we are used to on this forum and many people wrote their stories of long crash after taking these supplements. I just don't want to contrubite to any event of such nature. In the end these who decide to try these regimens are actual living individuals, in desperate position to do anything to help themselves, they should not be experimented on or be taken advantage from. Writing the topic that i would like to write, without doing it carefully and without necessary precautions would be unresponsible, at least that is my opinion.

The second problem is that i can not give some "5 steps how to cure PSSD" and write "point 1. take inositol", because it will just not work on universal scale, as of why , I will write in the actual post. Some wrote topics praising inositol for curing them, others were writing inositol crashed them for quite a long time. How is this possible that the difference between 2 individuals is going in like 2 opposite ways? one would understand that the factor that would be masured is the strenght of efficiacy: like some benefit fully and got cured, others benefit a little bit but not a big deal, but not the total opposite, that some are cured, while other not only aren't cured but also feel way worse. That is very counterintuitive to say the least. The part about me holding back: I will not hold back anything I know in the post that i plan in the future, at least from practical standpoint. I did so before but these were really unsave things. I just realized in the middle of writing that post that my past posts were written in not justifably cheerful way. I was really not all that informed on the subject at the time, compared to what I am now and I wanted to tone the hype regarding this future post to reasonable degree, where people will be looking up to the new post but nothing more, it also takes pressure off of me a bit.

I completely understand your sentiment about my previous posts, they were not the best quality, but as my knowledge expanded i understand those shoots were on "ok" level for the amount of information i possesed at the time. What i really want to do is to deepen people understanding of PSSD, deepen the understanding of various protocols people used in the past and why it worked in some and not in others etc, how to use these informations to potentially help yourself and more. I still face significant challenges, but I think that when people will see how interconnected things are between the every supplement mentioned on this forum and their respective effects on PSSD symptoms - and their cellular mechanism involved, then they will jump to the same conclusions as I did.

I may even make some tl:dr later on this week, with only etiology department, because that pretty much I do not need to actively work anymore or at least not as much, and the practical stuff leave for after I will be fully ready. And i think I would like you to know beforehand that the answer will not be of kind like : ,,PSSD is misfolded WNT1 protein", or anything like that. It will be as practical as it can be to justify to you that certain regimens did indeed had the right to work, their pharmacological interconnections, etc.

I am sorry if this post does not resort to the standard of clarity that you may otherwise have but I am really tired and heading straight to sleep after submitting this post. In the end my confidence this time stems from practical reasons: I am able to induce certain effects and predict them happening beforehand. Since idea matches reality I gain confidence that my approach is right/closer to the truth, while people who wrote about PSSD in the past (myself included) were wrong.
Last edited by guacamo on Fri Nov 25, 2022 9:58 pm, edited 1 time in total.
JakeLawe
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Re: Everything we knew about PSSD is wrong. Check out why.

Unread post by JakeLawe »

Man, you guys need to learn to use paragraphs, seriously.

Every school should teach the importance of using paragraphs when writing online . Nobody and I mean, NOBODY gonna read a wall of text. Ok, maybe masochists.

You see it everywhere, specially reddit. People don't bother to use paragraphs and then wonder why they don't get any reply! or why no one takes them seriously.

Is right there.. a space bar.. horizontal.. bigger than any other key. The brain rests, the eyes rests, looks beautiful. Commas, periods, paragraphs.. capital letters. What a world could be to only even attempt it!

Just saying.
bupropioninducedPSSD
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Re: Everything we knew about PSSD is wrong. Check out why.

Unread post by bupropioninducedPSSD »

I for one would be very interested to see your thread. Thank you for bringing all of this research and knowledge to the community.
HzeTmy
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Re: Everything we knew about PSSD is wrong. Check out why.

Unread post by HzeTmy »

What if our immune system fights serotonin anyone came to that idea ? Leaky gut, gut problems - immune system overreaction.
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