Compared to previous SSRI use, how do you feel listening to music?

[sadKeanu]

.

[PLZNO]

So.. I'm not the only one who felt this
The music became less addictive
I can still enjoy it
But less addictive
I don't know It's pssd related though

[DoIt]

As i wrote in the other thread... But people don't seem to take it seriously...
Fucked opioid system is the cause for this..

Many of us also report no enjoyment in music, so here's a study that shows how music uses the same reward pathways as sexual pleasure among others. When they blocked μ-opioid receptors with NTX, people couldn't enjoy music as before.

Therefore we can conclude that μ-opioid receptors play a major role in expiriencing pleasure.


Anhedonia to music and mu-opioids: Evidence from the administration of naltrexone

We conclude that endogenous opioids are critical to experiencing both positive and negative emotions in music, and that music uses the same reward pathways as food, drug and sexual pleasure.

Our primary hypothesis was based on the previous literature which illustrated the role of endogenous opioids in mediating food, drug, and sex pleasure25,26,35,37,49,50; we predicted that blocking μ-opioid receptors with NTX would cause decreased physiological reactions to music for both positive and negative emotions. This was confirmed for both pleasurable and neutral music, compared to placebo, through EMG recordings of two different facial muscles (Fig. 1), supporting the NTX-induced anhedonia hypothesis.

We have shown here that the opioid system is responsible for mediating the elicitations of both positive (pleasurable) and negative (sadness) emotional responses to music.

http://www.nature.com/articles/srep41952#results

[Bigmum]

Yes even on Rxisk there is a mention that some people have at least short term benefits from LDN....

[raven100]

DoIt but could these receptors be responsible for a more general anhedonia too? Seeing as a considerable number of us have anhedonia isn't it more likely that whatever is causing that anhedonia is responsible for any music-anhedonia

[DoIt]

DoIt but could these receptors be responsible for a more general anhedonia too? Seeing as a considerable number of us have anhedonia isn't it more likely that whatever is causing that anhedonia is responsible for any music-anhedonia

Yes, they are resposible for anhedonia in general, see:

We conclude that endogenous opioids are critical to experiencing both positive and negative emotions in music, and that music uses the same reward pathways as food, drug and sexual pleasure.

And anhedonia is the core symptom of PSSD, no pleasure equals no libido, no arousal, no enjoyment.