A forum dedicated to collaborative research into PSSD (Post-SSRI Sexual Dysfunction).
https://www.pssdforum.org/
My bet is those cases are vulnerable to begin with and the acute doses increase cortisol aswell, add oxidative stress + nmda rebound + opioid withdrawal from venlafaxin to it and will lead to this cascade of mitochondrial damage.
You can keep arguing in support of this, but then you would have to apply it in practice. If you believe your theory, you should start taking MitoQ then and honestly record your experience in this thread. I don't think you should try to get SS-31 as you said in the other thread since it's not yet approved for use in people.
MitoQ can cause mitochondrial swelling: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880956/defmyst wrote: ↑Wed Aug 19, 2020 3:37 pmYou can keep arguing in support of this, but then you would have to apply it in practice. If you believe your theory, you should start taking MitoQ then and honestly record your experience in this thread. I don't think you should try to get SS-31 as you said in the other thread since it's not yet approved for use in people.
I don't understand your logic. Because this paper says that MitoQ might produce mitochondrial swelling (while SS-31 does not) you are willing to take SS-31 when the drugs is still in clinical trials? You do realize that there hundreds of different ways a substance can affect the body that scientists may not know about hence the clinical trials. Besides, this paper states that MitoQ should not be given to people who already have problems with their kidneys. There is also no discussion on how extensive/severe the potential damage is or whether the effect is permanent or kidney cells heal themselves after discontinuation of MitoQ.cdraham wrote: ↑Wed Aug 19, 2020 3:53 pmMitoQ can cause mitochondrial swelling: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880956/defmyst wrote: ↑Wed Aug 19, 2020 3:37 pmYou can keep arguing in support of this, but then you would have to apply it in practice. If you believe your theory, you should start taking MitoQ then and honestly record your experience in this thread. I don't think you should try to get SS-31 as you said in the other thread since it's not yet approved for use in people.
I do realize its still in clinical trials, i just found it interesting that MitoQ could cause this will Ss-31 did not. Its true that a substance can affect the body in hundreds of different ways that scientists dont know of, thats the reason we are here. People on this forum try injecting hormones and take parkinson/alzheimer drugs which are probably much more dangerous than taking this peptide. But this is just my unscientific guess.defmyst wrote: ↑Wed Aug 19, 2020 4:54 pmI don't understand your logic. Because this paper says that MitoQ might produce mitochondrial swelling (while SS-31 does not) you are willing to take SS-31 when the drugs is still in clinical trials? You do realize that there hundreds of different ways a substance can affect the body that scientists may not know about hence the clinical trials. Besides, this paper states that MitoQ should not be given to people who already have problems with their kidneys. There is also no discussion on how extensive/severe the potential damage is or whether the effect is permanent or kidney cells heal themselves after discontinuation of MitoQ.cdraham wrote: ↑Wed Aug 19, 2020 3:53 pmMitoQ can cause mitochondrial swelling: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5880956/defmyst wrote: ↑Wed Aug 19, 2020 3:37 pm
You can keep arguing in support of this, but then you would have to apply it in practice. If you believe your theory, you should start taking MitoQ then and honestly record your experience in this thread. I don't think you should try to get SS-31 as you said in the other thread since it's not yet approved for use in people.
Is it mitochondria targeted?